Comparative Study of Intra Operative Blood Sugar Level in Spinal Anesthesia and General Anesthesia in Patients undergoing Elective Surgery

Abstract

Introduction: The aim of the study was to carry out the comparative study of variations in blood glucose levels intra operatively in patients undergoing surgical procedures in Spinal Anesthesia and General Anesthesia by capillary blood glucose level.Objective: To compare intra operative blood glucose level in Spinal and General Anesthesia.Methodology: Sixty non diabetic patients (30 in each group) aged between 20 – 60 years belonging to ASA I and ASA II status were enrolled for this prospective comparative study. Capillary blood glucose was measured preoperatively and thereafter at 15 minutes interval after incision in Spinal Anesthesia and after induction of General Anesthesia till one hour of surgery. For statistical analysis paired sample t – test was used for comparing mean of quantitative data. Difference was considered statistically significant if p < 0.05.Results: Blood sugar level was well controlled in patients receiving spinal anesthesia. General anesthesia produced more increase in blood sugar level compared to base line value which was statistically significant (P<0.05). Similarly, Glycaemia was significantly higher in the General anesthesia group (p < 0.05) when compared with Spinal Anesthesia group suggesting poor control of stress response during general anesthesia.Conclusion: Based on capillary blood glucose level, spinal anesthesia proved more effective in suppressing stress response as compared to general anesthesia in elective surgical patients. BJHS 2018;3(2)6: 458-462

Comparison of spinal versus general anesthesia on the perioperative blood glucose levels in patients undergoing lower abdominal and pelvic surgery: a prospective cohort study, Ethiopia

“…In contrast to our study, a study conducted by Bajracharya et al . 19 found in patients who underwent elective surgery under SA, each measurement of intraoperative blood glucose levels at different time intervals was slightly decreased from baseline value without significant difference ( P >0.05). Another study also found that there is no significant change in blood glucose levels from a baseline value throughout a procedure in both diabetic mellitus and Non-diabetic mellitus patients undergoing hip surgery under SA 32 .…”

“…The sample size was calculated using a comparison of two means in the formula for continuous outcomes with equal sample size; based on a previous study done in Nepal 19 which showed, the mean and standard deviation of the mean blood glucose level in the GA group is (86.32±12.3 mg/dL) and in SA group is (95.36±14.15 mg/dL), with µ 1= 86.32, σ 1= 12.3 and µ 2= 95.36, σ 2= 14.1, and with an alpha error of 0.05 at a power of 80%.…”

A Comparative Study of the Tolerance to Stress Response Under Spinal Anaesthesia in Diabetic Versus Non-Diabetic Patients

“…Previous studies have shown that heat tolerance is impaired in obese patients. 24 Perioperative hypothermia in patients with DAN may be associated with the disability of the body to increase heat production by metabolic factors or decrease blood flow to the skin via vasoconstriction. 22 Autonomic neuropathy may slow down the onset of feedback thermoregulatory constriction of blood vessels and may diminish its effectiveness once activated.…”