Comparative study of serum 6-hydroxy-5-methoxyindole-2-carboxylic acid, 5-S-cysteinyl-dopa, and lactate dehydrogenase levels as markers for malignant melanoma
Hiroshi Umemura,
Masaki Takiwaki,
Yoshikuni Kikutani
et al.
Abstract:Background
With the development of novel therapies for advanced malignant melanoma (MM), biomarkers that can accurately reflect the progression of MM are needed. Recently, we have developed a method to measure the serum levels of 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C), a melanin-related metabolite, using mass spectrometry and reported that it may be a potential marker for MM.
Objective
In the present study, we compared the usefulness of serum levels of 6H5MI2C, 5-S-cysteinyl-dopa (5-S-CD), and… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.