Comparative study of serum fasting blood glucose level, insulin resistance, serum thyroid stimulating hormone level, serum ferritin level and serum gama amino butyric acid level in diagnosed polycystic ovarian syndrome patients

Abstract

Aim and Objective: To evaluate to evaluate the levels of Serum Fasting blood glucose, IR, Serum TSH, Serum Ferritin and Serum GABA in diagnosed PCOS patients and normal controls. Methods: The study was conducted on 160 subjects aged between 18 to 45 years comprising of 80 healthy control and 80 patients with clinically diagnosed cases of PCOS, acted as study group. The blood samples of controls as well as study groups were withdrawn and Clinical evaluation included anthropometry, Height, Weight, Body Mass Index (BMI) and waist-to-hip ratio (WHR) were calculated. Circulating levels of fasting glucose, insulin resistance, Serum Thyroid stimulating hormone level, Serum Ferritin level and Serum Gama amino butyric acid level were determined by Chemiluminescence based immunoassay (CLIA) on fully automated Biochemistry analyzer MAGLUMI 1000. Results: Total 160 subjects with both control and study group PCOS patients were included in the study. The age of these control group was ranged from 18 to 45 years, with a mean of 26.23±5.58 years and PCOS study were found 27.76 ±6.54 years. The findings of anthropometric measurements of the subjects of both PCOS syndrome (n=80) and non-PCOS (n=80).