Comparative study of single versus multiple gallstone disease in KGH, Visakhapatnam

Raja, C. Dharma Kishore; Keerthi, Dondapati; Kiran, Adikari Sai; Aravind, Gunto; Raja, Sreerama; Karthik, G. Manoj; Sreenija, Devarakonda; Kumar, N

doi:10.18203/2349-2902.isj20204139

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…Similar to our study, Raja et al also reported that surgeons encountered greater difficulty during LC among patients having multiple gallstones. 15 In the multiple gallstones, the small floating stones may not remain in constant touch with the gallbladder mucosa, thereby spreading the inflammation to multiple sites inside the gallbladder. Because the gallbladder and extrahepatic bile duct are drained by lymphatic vessels and lymph nodes in Calot's triangle and along the bile duct, its inflammation results in the formation of adhesions around Calot's triangle and the common duct.…”

Section: Discussionmentioning

confidence: 99%

“…14 Whereas other studies suggest that multiple stones are more harmful. 15,16 The inflammation and the pathological factors influenced by the number of stones in GB are associated with higher odds of conversion of LC to OC. 10,11 Thus, this study was conducted to investigate and identify clinical, haematological, radiological factors and surgical outcomes associated with single versus multiple gallstones.…”

Section: Introductionmentioning

confidence: 99%

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Clinical presentation and surgical outcome among patients having single and multiple gallstones: a prospective study

Baghel¹,

Anand²,

Gupta³

2022

Int Surg J

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Background: Outcome of laparoscopic cholecystectomy is determined by an array of factors including patient & gallstone-related variables. Number of gallstones influences pathophysiology of disease thereby influencing outcome of surgery. This study was aimed at investigating clinical, haematological, radiological features and surgical outcomes among patients having single and multiple gallstones. Methods: Single centre, hospital-based, prospective, observational study involving 60 patients undergoing LC. Data pertaining to clinical, hematological, radiological variables and surgical outcomes were collected and analysed.Results: Mean duration of symptoms (m/c- pain) was significantly shorter among participants having multiple gallstones (p=0.034). There was no statistically significant difference among participants having single and multiple stones regarding any of clinical signs and symptoms (p>0.05). Mean GB wall thickness among patients having single and multiple gallstones was 3.27 mm and 4.18 mm (p=0.038). Difference in proportion of patients having pericholecystic collections was statistically significant (p=0.019). Mean duration of surgery among participants with single and multiple stones was 57 minutes and 71 minutes, respectively (p=0.012). On intraoperative examination, adhesion was noted in 20% of participants with single stone and 35% of participants in multiple stones group (p=0.029). Conversion rate to OC was 12% in multiple stones group and only 3.4% of participants with single stone (p=0.028). Adjusted odds ratio for conversion to OC was 3.39 (95% CI 1.98-7.89) for patients having multiple gallstones.Conclusions: Although patients having single and multiple gallstones have similar clinical features, findings of ultrasonography and surgical outcomes may differ significantly.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical presentation and surgical outcome among patients having single and multiple gallstones: a prospective study

Baghel¹,

Anand²,

Gupta³

2022

Int Surg J

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“…Other symptoms were dyspepsia seen in 25% and 30%, nausea/ vomiting in 45% and 38% in group 1 and 2 patients respectively. A study by Zhang et al, [17] suggested that LC is the gold standard in the treatment for cholelithiasis. Prophylactic cholecystectomy is justified only high suspicion of life.…”

Section: Discussionmentioning

confidence: 99%

Single versus multiple gall stone disease in patients undergoing laparoscopic cholecystectomy

Singh¹,

Sharma²

2021

TCMS

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The aim of this paper is to compare single versus multiple gall stone disease in patients undergoing laparoscopic cholecystectomy. A total of one hundred and thirty patients (males- 52, females- 78) within age group 20-65 years presented with cholelithiasis were divided into 2 groups. Group 1 comprised of single stone patients and group II had multiple stones. Each group had 65 patients. Parameters compared were symptoms and operative findings between both groups, Analysis of results was carried with chi0 square test. Most common clinical symptoms found to be fever in both groups (87%- group 1, 90%- group 2). Other symptoms were dyspepsia seen in 25% and 30%, nausea/ vomiting in 45% and 38% in group 1 and 2 patients respectively. Females were commonly affected and maximum case were observed in age group 40-50 years. Multiple gall stones patients had more symptoms and prevalence of conversion to open surgery was more in these patients. Group 1 patients showed gall bladder distention in 56 and group 2 in 62 patients, gall bladder contraction was seen in 6 patients in group 1 and 3 in group 2, adhesions were exhibited by 11 patients in group 1 and 20 in group 2. 4 patients in group 2 converted to open surgery. Gangrenous gall bladder was seen in 1 in group 1 and 5 in group 2.

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Comparative study of single versus multiple gallstone disease in KGH, Visakhapatnam

Cited by 2 publications

References 4 publications

Clinical presentation and surgical outcome among patients having single and multiple gallstones: a prospective study

Clinical presentation and surgical outcome among patients having single and multiple gallstones: a prospective study

Single versus multiple gall stone disease in patients undergoing laparoscopic cholecystectomy

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