Photovoltaic (PV) systems are among the types of renewable energy that are frequently employed. Since the characteristics of the solar cell depend on the amount of insolation and temperature, it is necessary to use MPPT “Maximum Power Point Tracking” to move the operating voltage close to the maximum power point under changing weather conditions. This article aims to design a photovoltaic energy system based on boost converter control to obtain maximum power using a hybrid algorithm based on artificial neurons (ANN). Additionally included is a proportional-integral (PI) controller, which improves the performance of the ANN-MPPT controller; this method is quick and precise for tracking the maximum power point (MPP) in the face of variations in temperature and solar radiation. The efficiency of the tracking algorithm was calculated and compared to one of the traditional methods, the incremental conductance (INC) method, in addition to comparing it to other hybrid methods and by simulating the system using MATLAB/Simulation and analyzing the results. This study unequivocally proves the superiority of the hybrid ANN+PI strategy; the efficiency reached 99.91%. This approach excels at tracking maximum power accuracy by leveraging the adaptive learning capabilities of neural networks, ensuring maximum power even in the face of changing environmental conditions.