“…Although direct research that evaluated the association between hormone variability and the development of cancer was not published, hormonal disturbance may be served as the mediator between development of cancer and glycemic variability. The association between glycemic variability and hormonal disturbance was previously reported, even though it is still in controversy whether change of hormone may cause glycemic disturbance [34,35], or vice versa [36]. In terms of the association between variability in hormone and cancer, it was also previously reported [37].…”