Comparative study on the potentialities of two halophytic species in the green synthesis of gold nanoparticles and their anticancer, antioxidant and catalytic efficiencies

Hosny, Mohamed; Fawzy, Manal; Abdelfatah, Ahmed M.; Fawzy, Esraa E.; Eltaweil, Abdelazeem S.

doi:10.1016/j.apt.2021.07.008

Cited by 77 publications

(23 citation statements)

References 107 publications

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“…They emit a signal, also called the absorption peak or band, in the ultraviolet-visible spectrum. This signal appears between 500-600 nm, depending on the physical characteristics of the nanoparticles, such as size, shape, and concentration [20,34].…”

Section: Resultsmentioning

confidence: 99%

Green Synthesis of Homogeneous Gold Nanoparticles Using Sargassum spp. Extracts and Their Enhanced Catalytic Activity for Organic Dyes

López-Miranda

Molina

Esparza

et al. 2021

Toxics

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Sargassum species-based extracts were used to carry out the synthesis of homogeneous gold nanoparticles. Various techniques were used to determine the characteristics and composition of the nanoparticles. The UV-Vis results showed that the 50% water/ethanol extract had the most reducing agents and stabilizers. Therefore, this type of extract was used to synthesize nanoparticles and for their subsequent characterization. Crystallinity and crystal size were evaluated using X-ray diffraction. Size and morphology were analyzed using scanning electron microscopy, showing that the gold nanoparticles were mostly spherical, with a size range of 15–30 nm. The catalytic activity of the gold nanoparticles was evaluated through the degradation of organic dyes: methylene blue, methyl orange, and methyl red. The degradation rates were different, depending on the nature of each dye, the simplest to degrade was methylene blue and methyl red was the most difficult to degrade. The results indicated that the use of Sargassum spp. for the synthesis of gold nanoparticles has potential in the remediation of water that is contaminated with organic dyes. Moreover, given the recent serious environmental and economic problems caused by the overpopulation of Sargassum spp. in the Mexican Caribbean, the findings hold promise for their practical and sustainable use in the synthesis of nanomaterials.

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Section: Resultsmentioning

confidence: 99%

Green Synthesis of Homogeneous Gold Nanoparticles Using Sargassum spp. Extracts and Their Enhanced Catalytic Activity for Organic Dyes

López-Miranda

Molina

Esparza

et al. 2021

Toxics

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“…Vitamin C (ascorbic acid) was employed as a positive control. The activity was measured by the following equation 109 , 110 where control absorbance is the absorbance in the absence of antioxidants and sample absorbance is the absorbance in the presence of antioxidants (AuNPs, rGO-AuNPs, or vitamin C) at 517 nm.…”

Section: Methodsmentioning

confidence: 99%

Catalytic and Medical Potential of a Phyto-Functionalized Reduced Graphene Oxide–Gold Nanocomposite Using Willow-Leaved Knotgrass

et al. 2021

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In the current study, a simple, environmentally friendly, and cost-effective reduced graphene oxide–gold nanoparticle (rGO-AuNP) nanocomposite was successfully phytosynthesized using the aqueous leaf extract of a common weed found on the Nile banks, Persicaria salicifolia , for the first time. The phytosynthesis of rGO-AuNPs was first confirmed via the color transformation from brown to black as well as throughvarious techniques such as transmission electron microscopy (TEM) and Raman spectroscopy. Two UV–vis peaks at 275 and 530 nm were observed for the nanocomposite with a typical particle size of mostly spherical AuNPs of 15–20 nm. However, other shapes were occasionally detected including rods, triangles, and rhomboids. Existing phytoconstituents such as flavonoids and glycosides in the plant extract were suggested to be responsible for the phytosynthesis of rGO-AuNPs. The excellent catalytic efficacy of rGO-AuNPs against MB degradation was confirmed, and a high antibacterial efficiency against Escherichia coli and Klebsiella pneumonia was also confirmed. Promising antioxidant performance of rGO-AuNPs was also proved. Furthermore, it was concluded that rGO-AuNPs acquired higher efficiency than AuNPs synthesized from the same plant extract in all of the studied applications.

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“…AuNPs were prepared in a single-step method, and the anticancer efficacies of A. halimus -AuNPs and C. amperosidies -AuNPs were investigated in the MCF-7 cancer cell line via an MTT assay. It was observed that the efficiency of A. halimus -AuNPs (IC50 = 47.03 μg/mL) in inhibiting the growth of cancer cells was higher than that of C. amperosidies -AuNPs (IC50 = 22 μg/mL) [ 152 ]. AuNPs synthesized using dragon fruit extract showed significant anti-proliferative activity against MCF-7 and MDA-MB-231 cells using an Alamar blue assay.…”

Section: Green Synthesis Of Aunps For Cancer Theranosticsmentioning

confidence: 99%

Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis

et al. 2022

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Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precursors used in plant-based synthesized AuNPs allows for the development of large-scale production in a greener manner. Conventional cancer therapies, such as surgery and chemotherapy, have significant limitations and frequently fail to produce satisfying results. AuNPs have a prolonged circulation time, allow easy modification with ligands detected via cancer cell surface receptors, and increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies have been carried out on the use of AuNPs as contrast agents for X-ray-based imaging techniques (i.e., computed tomography). As nanocarriers, AuNPs synthesized by nontoxic and biocompatible plants to deliver therapeutic biomolecules could be a significant stride forward in the effective treatment of various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using Medicago sativa, Olax Scandens, H. ambavilla, and H. lanceolatum, have been used in detecting cancers. Moreover, green synthesized AuNPs using various extracts have been applied for the treatment of different types of solid tumors. However, the cytotoxicity of AuNPs primarily depends on their size, surface reactivity, and surface area. In this review, the benefits of plant-based materials in cancer therapy are firstly explained. Then, considering the valuable position of AuNPs in medicine, the application of AuNPs in cancer therapy and detection is highlighted with an emphasis on limitations faced by the application of such NPs in drug delivery platforms.

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Comparative study on the potentialities of two halophytic species in the green synthesis of gold nanoparticles and their anticancer, antioxidant and catalytic efficiencies

Cited by 77 publications

References 107 publications

Green Synthesis of Homogeneous Gold Nanoparticles Using Sargassum spp. Extracts and Their Enhanced Catalytic Activity for Organic Dyes

Green Synthesis of Homogeneous Gold Nanoparticles Using Sargassum spp. Extracts and Their Enhanced Catalytic Activity for Organic Dyes

Catalytic and Medical Potential of a Phyto-Functionalized Reduced Graphene Oxide–Gold Nanocomposite Using Willow-Leaved Knotgrass

Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis

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