Comparative study on the self-assembly of pectin and alginate molecules regulated by calcium ions investigated by atomic force microscopy

Wang, Hui; Fei, Shengying; Wang, Yifei; Liu, Zan; Zhu, Jie

doi:10.1016/j.carbpol.2019.115673

Cited by 47 publications

(20 citation statements)

References 25 publications

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“…25 The high methoxy pectin in which galacturonic acid residues are in esterified form is aggregated mainly by a combination of non-specific hydrophobic interactions of the ester methyl groups and hydrogen bond, whereas the binding process of low methoxy pectin and alginate with Ca ions modifies the egg-box model. 26 Therefore, in our study, the lower amount of alginate in the feeding solution would provide fewer cross-linking points and a looser structure with larger beads. Also, it was reported that the weaker mechanical stability of the possible calcium pectinate network would increase the size of alginate-pectin gel mixed beads.…”

Section: Particle Size and Morphology Of Beadsmentioning

confidence: 78%

“…The binding behaviors of calcium ions to pectin and alginate reveal structural influences and might have an influence on the bead properties 25 . The high methoxy pectin in which galacturonic acid residues are in esterified form is aggregated mainly by a combination of non‐specific hydrophobic interactions of the ester methyl groups and hydrogen bond, whereas the binding process of low methoxy pectin and alginate with Ca ions modifies the egg‐box model 26 . Therefore, in our study, the lower amount of alginate in the feeding solution would provide fewer cross‐linking points and a looser structure with larger beads.…”

Section: Resultsmentioning

confidence: 99%

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Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

et al. 2021

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BACKGROUND: Ellagic acid (EA), a potent dietary antioxidant, has limited bioavailability owing to its rapid absorption in the stomach and small intestine, and EA is transformed to more bioavailable compoundsurolithinsin the colon. An encapsulation system that sustains the release of EA in the gastrointestinal system and delivers more EA into the colon could improve the oral bioavailability of EA. Electrosprayed EA-loaded alginate-pectin beads were produced and coated with low-(LC) and highmolecular-weight chitosan (HC). The EA release from uncoated and coated beads under simulated gastrointestinal conditions was evaluated. The samples were characterized by particle size, gel strength, scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) analysis.RESULTS: The encapsulation efficiency (EE%) of EA ranged from 49.53% to 69.85% for uncoated beads, which was elevated up to 86.50% by coating, and LC coating provided higher EE%. Pectin addition to alginate and chitosan coating reduced the gel strength and changed the size depending on the molecular weight of chitosan. SEM images of pectin-added beads showed fewer cracks but more wrinkles, and chitosan coating presented more aggregated surfaces. The ionic interaction of alginatepectin-chitosan and the entrapment of EA were confirmed by FTIR. In the gastric medium, EA release was very low from uncoated beads (15.2-19.8%), and totally restricted by chitosan coating. In the intestinal stage, EA release from LC-coated alginate-pectin beads was only 18%, and it was between 55% and 65% for uncoated or HC-coated counterparts.CONCLUSION: The LC-coated alginate-pectin beads could be further explored as a potential system for colon-targeted delivery of EA.

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Section: Particle Size and Morphology Of Beadsmentioning

confidence: 78%

Section: Resultsmentioning

confidence: 99%

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

et al. 2021

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“…Inspired by nature, the hydrogel systems discussed herein adhesion groups [118, 121], high proportion of charged side chains [27], the balance of cohesion and adhesion and mechanical properties contribute to the tissue adhesion of natural polymer adhesive hydrogel [31–39, 162, 163, 173–175, 177–179]. As some natural hydrogels are composed of natural polymers derived from tissue components, in addition to biocompatibility, they are used in various fields such as nerve injury repair, bone repair, cartilage repair etc.…”

Section: Discussionmentioning

confidence: 99%

“…hydrogen bonds) and are highly directional and reversible. Typical alginate hybrid hydrogels composed of ionic cross-linked alginate chains and permeable elastic networks [34][35][36][37][38][39] have been widely reported to have ideal mechanical properties, self-healing properties, and biocompatibility. Zhang et al [34] constructed alginate-based double-cross-linked hydrogels by introducing ion crosslinking.…”

Section: Balance Of Cohesion and Adhesionmentioning

confidence: 99%

“…Hydrogels can be tailored to achieve various cross-linking densities, mechanical properties, and porous structures through various cross-linking mechanisms and functional groups. A significant amount of research has proposed integrating functional components or chemically/biologically active systems to form functional hydrogels, such as self-healing materials [31,[34][35][36][37][38][39][40], conductive fillers [41][42][43][44][45][46][47][48][49][50][51], and adhesion groups.…”

Section: Introductionmentioning

confidence: 99%

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Natural polymer‐based adhesive hydrogel for biomedical applications

Long

Xie

2022

Biosurface and Biotribology

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Hydrogel is a polymer network system that can form a hydrophilic three‐dimensional network structure through different cross‐linking methods. In recent years, hydrogels have received considerable attention due to their good biocompatibility and biodegradability by introducing different cross‐linking mechanisms and functional components. Compared with synthetic hydrogels, natural polymer‐based hydrogels have low biotoxicity, high cell affinity, and great potential for biomedical fields; however, their mechanical properties and tissue adhesion capabilities have been unable to meet clinical requirements. In recent years, many efforts have been made to solve these issues. In this review, the recent progress in the field of natural polymer‐based adhesive hydrogels is highlighted. The authors first introduce the general design principles for the natural polymer‐based adhesive hydrogels being used as excellent tissue adhesives and the challenges associated with their design. Next, their usages in biomedical applications are summarised, such as wound healing, haemostasis, nerve repair, bone tissue repair, cartilage tissue repair, electronic devices, and other tissue repairs. Finally, the potential challenges of natural polymer‐based adhesive hydrogels are presented.

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Pectin from Agro‐Waste Residues for Food Packaging

Mondal,

Katiyar

2024

Agro‐Waste Derived Biopolymers and Biocomposites

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Comparative study on the self-assembly of pectin and alginate molecules regulated by calcium ions investigated by atomic force microscopy

Cited by 47 publications

References 25 publications

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

Electrosprayed chitosan‐coated alginate–pectin beads as potential system for colon‐targeted delivery of ellagic acid

Natural polymer‐based adhesive hydrogel for biomedical applications

Pectin from Agro‐Waste Residues for Food Packaging

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