Comparative Tissue Reactivity to Topical Hemostatic Agents in the Periureteral Area

Effect of absorbable topical hemostatic agents on the relaxation time of blood: an in vitro study with implications for postoperative magnetic resonance imaging

“…The efficacy of different hemostatic agents has been evaluated in animals, 1,5,6,21,25 and tissue responses have been reported for a variety of sites. 7,18,19,24 In in vivo studies of hemostatic efficacy, collagen-based agents have generally proved superior to gelatin-and cellulose-based agents, despite different handling characteristics. 1,11,20,24 Comparative in vitro studies yielded a similar overall ranking: collagen-based agents (sponges or microfibrils) exceeded Gelfoam, which in turn worked more effectively than oxidized regenerated cellulose (Surgicel).…”

“…7,18,19,24 In in vivo studies of hemostatic efficacy, collagen-based agents have generally proved superior to gelatin-and cellulose-based agents, despite different handling characteristics. 1,11,20,24 Comparative in vitro studies yielded a similar overall ranking: collagen-based agents (sponges or microfibrils) exceeded Gelfoam, which in turn worked more effectively than oxidized regenerated cellulose (Surgicel). 23 Oxidized regenerated cellulose (Surgicel), a homogeneous soft knitted gauze, is the absorbable topical hemostatic agent preferred in cranial surgery.…”

Regenerative Treatment for Soft Tissue Defects of the External Auditory Meatus

“…Gelatin sponge is made of a protein extracted from the collagen found inside the connective tissues of animals and is often used for its hemostatic properties in medical procedures (15). Gelatin sponge has a high affinity for living tissues and is absorbable in vivo within a few months.…”

“…These characteristics of gelatin sponge make it particularly advantageous for use in regenerating BDs of the EAM. As a final consideration, it is also very important to optimize the regenerative conditions (5,15,16). In the last step of our procedure, we seal the gelatin sponge with a fibrin glue to insulate it from the outside creating optimal regenerative conditions.…”

Celulosa oxidada (Surgicel®) simulando un absceso después de nefrectomía parcial laparoscópica

“…Aunque es preferible retirar la gasa de celulosa oxidada una vez se consigue la hemostasia deseada, puede dejarse intencionadamente en el campo quirúrgico (para facilitar la hemostasia o como rutina preventiva, para evitar el rezumado hemático post-operatorio, tal como se recomienda para la hemostasia del lecho de la nefrectomía parcial laparoscópica), pues se absorbe sin causar reacción fibrótica o inflamatoria significativa, ni aún en presencia de orina estéril 4 . Pequeñas colecciones de aire atrapados en el intersticio de la gasa pueden detectarse hasta más de un mes después de la intervención 2 , y podrían confundirse con un absceso bacteriano, aunque en éste el número de burbujas de gas suele ser más numeroso y es típica la existencia de niveles hidroaéreos.…”