Comparing baseline symptom severity and demographics over two time periods in an outpatient palliative radiotherapy clinic

Khan, Luluel; Kwong, Justin; Nguyen, Janet; Chow, Edward; Zhang, Liying; Culleton, Shaelyn; Zeng, Liang; Jon, Florencia; Tsao, May; Barnes, Elizabeth; Danjoux, Cyril; Sahgal, Arjun; Holden, Lori

doi:10.1007/s00520-011-1120-1

Cited by 16 publications

(14 citation statements)

References 29 publications

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“…Previous studies had compared symptom burden in different diagnosed patients, 22 in different stages of disease, 13 in different treatments, 23,24 and in different time periods. 25 There were only few studies that reported symptom burden in cancer patients with cachexia. In the validation study of consensus definition of cancer cachexia, patients in different cachexia stages reported different severity scores in pain, fatigue, nausea, drowsiness, and lack of appetite, and no difference was seen in depression.…”

Section: Discussionmentioning

confidence: 99%

Differences in Symptom Burden Among Cancer Patients With Different Stages of Cachexia

Zhou

Yang

Thapa

et al. 2017

Journal of Pain and Symptom Management

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Section: Discussionmentioning

confidence: 99%

Differences in Symptom Burden Among Cancer Patients With Different Stages of Cachexia

Zhou

Yang

Thapa

et al. 2017

Journal of Pain and Symptom Management

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“…MPCTs have been established in many hospitals with radiotherapy facilities, and such teams often provide additional supportive care interventions [10], physical exercise and therapy [11], and spiritual care, focusing on patients and caregivers [12], but their influence on pattern of care and outcomes has not been studied extensively. Pituskin et al reported on multidisciplinary assessment of patients with symptomatic bone metastases attending a dedicated outpatient palliative radiotherapy clinic [13].…”

Section: Discussionmentioning

confidence: 99%

Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison

et al. 2014

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Purpose. To analyze pattern of care and survival after palliative radiotherapy (RT) in patients managed exclusively by regular oncology staff or a multidisciplinary palliative care team (MPCT) in addition. Methods. Retrospective analysis of 522 RT courses. Comparison of Two Groups: MPCT versus none. Results. We analyzed 140 RT courses (27%) with MPCT care and 382 without it. The following statistically significant differences were observed: 33% of female patients had MPCT care versus only 23% of male patients and 37% of patients <65 years had MPCT care versus only 22% of older patients. MPCT patients were more likely to have poor performance status and liver metastases. In the MPCT group steroid and opioid use was significantly more common. Dose-fractionation regimens were similar. Median survival was significantly shorter in the MPCT group, 3.9 versus 6.9 months. In multivariate analysis, MPCT care was not associated with survival. Adjusted for confounders, MPCT care reduced the likelihood of incomplete RT by 33%, P > 0.05. Conclusions. Patterns of referral and care differed, for example, regarding age and medication use. It seems possible that MPCT care reduces likelihood of incomplete RT. Therefore, the impact of MPCT care on symptom control should be investigated and objective referral criteria should be developed.

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“…ESAS was used rather than its modified version (ESAS-r) because it has more established validity and reliability reports 9–11 33 36…”

Section: Methodsmentioning

confidence: 99%

Systematic bias in cancer patient-reported outcomes: symptom ‘orphans’ and ‘champions’

Thomas

Walsh

Aktaş

2015

BMJ Support Palliat Care

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Of 46 checklist cancer symptoms, over a third were orphans. All orphan symptoms were rated as clinically important and distressing by checklist. Only 5 checklist symptoms were champions: fatigue, pain, anorexia, dyspnoea and nausea. Important-but usually omitted-symptoms included early satiety (6 of 6) and weight loss (5 of 6). The bias appears to disproportionately affect gastrointestinal and neuropsychiatric symptoms. Symptom studies should specifically report the limitations and account for the inherent item bias of any instrument used.

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Comparing baseline symptom severity and demographics over two time periods in an outpatient palliative radiotherapy clinic

Cited by 16 publications

References 29 publications

Differences in Symptom Burden Among Cancer Patients With Different Stages of Cachexia

Differences in Symptom Burden Among Cancer Patients With Different Stages of Cachexia

Palliative Radiotherapy with or without Additional Care by a Multidisciplinary Palliative Care Team: A Retrospective Comparison

Systematic bias in cancer patient-reported outcomes: symptom ‘orphans’ and ‘champions’

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