Comparing effects of continuous glucose monitoring systems (CGMs) and self-monitoring of blood glucose (SMBG) amongst adults with type 2 diabetes mellitus: a systematic review protocol

Zheng, Miaoyan; Luo, Yunting; Lin, Wei; Khoja, Adeel; Yang, Shuo; Zhao, Xuan; Hu, Peng

doi:10.1186/s13643-020-01386-7

Cited by 11 publications

(8 citation statements)

References 34 publications

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“…Previous reviews on diabetes technology have mostly focused on the effectiveness or efficacy of the technology in adult populations [26][27][28], with some also including youth [29]. While various studies have focused on experiences with diabetes technology and particularly experiences with technology in young people with T1DM, reviews of such study findings are still lacking.…”

Section: Technology For Diabetes Managementmentioning

confidence: 99%

Experiences of Young People and Their Caregivers of Using Technology to Manage Type 1 Diabetes Mellitus: Systematic Literature Review and Narrative Synthesis

Brew‐Sam¹,

Chhabra²,

Parkinson³

et al. 2021

JMIR Diabetes

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Background In the last decade, diabetes management has begun to transition to technology-based care, with young people being the focus of many technological advances. Yet, detailed insights into the experiences of young people and their caregivers of using technology to manage type 1 diabetes mellitus are lacking. Objective The objective of our study was to describe the breadth of experiences and perspectives on diabetes technology use among children and adolescents with type 1 diabetes mellitus and their caregivers. Methods This systematic literature review used integrated thematic analysis to guide a narrative synthesis of the included studies. We analyzed the perspectives and experiences of young people with type 1 diabetes mellitus and their caregivers reported in qualitative studies, quantitative descriptive studies, and studies with a mixed methods design. Results Seventeen articles met the inclusion criteria, and they included studies on insulin pump, glucose sensors, and remote monitoring systems. The following eight themes were derived from the analysis: (1) expectations of the technology prior to use, (2) perceived impact on sleep and overnight experiences, (3) experiences with alarms, (4) impact on independence and relationships, (5) perceived usage impact on blood glucose control, (6) device design and features, (7) financial cost, and (8) user satisfaction. While many advantages of using diabetes technology were reported, several challenges for its use were also reported, such as cost, the size and visibility of devices, and the intrusiveness of alarms, which drew attention to the fact that the user had type 1 diabetes mellitus. Continued use of diabetes technology was underpinned by its benefits outweighing its challenges, especially among younger people. Conclusions Diabetes technologies have improved the quality of life of many young people with type 1 diabetes mellitus and their caregivers. Future design needs to consider the impact of these technologies on relationships between young people and their caregivers, and the impact of device features and characteristics such as size, ease of use, and cost.

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Section: Technology For Diabetes Managementmentioning

confidence: 99%

Experiences of Young People and Their Caregivers of Using Technology to Manage Type 1 Diabetes Mellitus: Systematic Literature Review and Narrative Synthesis

Brew‐Sam¹,

Chhabra²,

Parkinson³

et al. 2021

JMIR Diabetes

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“…To assess the variability in blood glucose levels, we selected a more representative and simple calculation of MBG, SDBG, MAGE, and HbA1c [18][19][20][21][22][23][24] . Wu et al [12] showed that blood glucose in the poor glycemic control group was higher at 10:30, with a downward trend to the lowest level at 12:30; blood glucose continued to rise to a peak at 14:30, then dropped to 16:30, and then rose again.…”

Section: Discussionmentioning

confidence: 99%

Establishment of blood glucose control model in diabetic mice

Rao¹,

Gao²,

Du³

et al. 2022

Int J Ophthalmol

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AIM: To explore the established method of the diabetic mouse blood glucose control model and preliminary observation of its influence on the retinas of diabetic mice. METHODS: The db/db BKS-DB (Leprko/ko) mice were randomly divided into two groups: the poor blood glucose control group (PG group, n=18) and the stable blood glucose control group (SG group, n=12), with BKS-DB (Leprwt/wt) as the normal blood glucose control group (NG group, n=18). According to the blood glucose values for 5 intervals which were monitored during the period of adaption, the PG group was injected with insulin aspart twice daily, fasted for 2h and then returned to normal. The SG group was injected with insulin aspart twice and insulin glargine once daily and fed with a quantitative ration. Fundus images were collected after eight weeks. The glycosylated hemoglobin (HbA1c), mean blood glucose level (MBG), standard deviation of blood glucose (SDBG), coefficient of variation of blood glucose (CVBG), and mean amplitude of glycemic excursion (MAGE) in each group were examined and calculated. RESULTS: The HbA1c, MBG, SDBG, CVBG, and MAGE levels in the PG group were significantly higher than those in the NG and SG groups (all P<0.05). MBG, SDBG, CVBG, and MAGE levels in the SG group were higher than those in the NG group (all P<0.05). There was no significant difference in HbA1c levels between the NG and SG groups (P>0.05). Preliminary observation of fundus images in the PG group and SG groups showed scattered retinal bleeding spots, while bleeding was more obvious in the PG group. CONCLUSION: The blood glucose control model of type 2 diabetes mellitus mice can be successfully established by subcutaneous injection of insulin aspart insulin glargine and rationed food, which is valuable for studying the mechanism of blood glucose fluctuations in diabetic complications in vivo.

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“…A systematic review still in press, the PROSPERO study [47], will compare the various forms of CGM systems (i.e. flash CGM, rtCGM, retrospective CGM) versus SMBG among adults with T2D.…”

Section: Cgm and T2dmentioning

confidence: 99%

Insulin pump therapy and continuous glucose monitoring in adults with type 2 diabetes: where are we now?

Pedone

Laurenzi

Allora

et al. 2020

Exploration of Medicine

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Technology in diabetes is rapidly evolving, with the aim of helping affected people to safely optimize their blood glucose control. New technologies are now considered as an essential tool for managing glycemia predominantly in people with type 1 diabetes, and clinical trials have demonstrated that in these subjects the use of continuous subcutaneous insulin infusion (CSII) and continuous glucose monitoring (CGM) systems are associated with improved glycemic control along with a better quality of life. Literature regarding technologies and type 2 diabetes is relatively lacking, but innovations may have an important role also in the management of these patients. Some studies in adults with type 2 diabetes have shown benefits with the use of CGM in terms of glycemic variability and improved therapeutic adjustments. Clinical trials about CSII and CGM use in type 2 diabetes may have some pitfalls and future studies are needed to assess how these advanced systems could improve clinical outcomes and also ensure cost-effectiveness in this population. In this narrative review, we aim to highlight the most relevant studies on this topic and to focus on the potential role of new technological devices in type 2 diabetes management.

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Comparing effects of continuous glucose monitoring systems (CGMs) and self-monitoring of blood glucose (SMBG) amongst adults with type 2 diabetes mellitus: a systematic review protocol

Cited by 11 publications

References 34 publications

Experiences of Young People and Their Caregivers of Using Technology to Manage Type 1 Diabetes Mellitus: Systematic Literature Review and Narrative Synthesis

Experiences of Young People and Their Caregivers of Using Technology to Manage Type 1 Diabetes Mellitus: Systematic Literature Review and Narrative Synthesis

Establishment of blood glucose control model in diabetic mice

Insulin pump therapy and continuous glucose monitoring in adults with type 2 diabetes: where are we now?

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