Comparing Operationalized Approaches for Substantial Reduction of Functioning in Chronic Fatigue Syndrome and Myalgic Encephalomyelitis

Elzbieta, Wiedbusch; A, Jason Leonard

doi:10.36959/547/653

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Substantial reduction in function was a self-report item in the DSQ in which persons responded to a binary item: "Since the onset of your problems with fatigue/energy, have your symptoms caused a 50% or greater reduction in your activity level?" This item has been found to be as accurate as longer scales to identify patients with a substantial reduction in functioning [40]. 48.8% of participants at time point 2 met the Canadian diagnostic criteria for ME/CFS.…”

Section: Case Definition For Me/cfsmentioning

confidence: 93%

Predictors of impaired functioning among long COVID patients

Jason

Dorri

2023

WOR

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BACKGROUND: There is limited information on what acute factors predict more long-term symptoms from COVID-19. OBJECTIVE: Our objective was to conduct an exploratory factor analysis of self-reported symptoms at two time points of Long COVID-19. METHODS: Data from patients with Long COVID-19 were collected at the initial two weeks of contracting SARS CoV-2 and the most recent two weeks, with a mean duration of 21.7 weeks between the two-time points. At time point 2, participants also complete the Coronavirus Impact Scale (CIS), measuring how the COVID-19 pandemic affected various dimensions of their lives (e.g., routine, access to medical care, social/family support, etc.). RESULTS: At time 1, a three-factor model emerged consisting of Cognitive Dysfunction, Autonomic Dysfunction and Gastrointestinal Dysfunction. The analysis of time 2 resulted in a three-factor model consisting of cognitive dysfunction, autonomic dysfunction, and post-exertional malaise. Using factor scores from time 1, the Autonomic Dysfunction and the Gastrointestinal Dysfunction factor scores significantly predicted the CIS summary score at time two. In addition, the same two factor scores at time 1 predicted the occurrence of myalgic encephalomyelitis/chronic fatigue syndrome at time 2. CONCLUSION: As Cognitive and Autonomic Dysfunction emerged as factors for both time points, suggesting health care workers might want to pay particular attention to these factors that might be related to later symptoms and difficulties with returning to pre-illness family life and work functioning.

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Section: Case Definition For Me/cfsmentioning

confidence: 93%

Predictors of impaired functioning among long COVID patients

Jason

Dorri

2023

WOR

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ME/CFS and Post-Exertional Malaise among Patients with Long COVID

Jason¹,

Dorri²

2022

Neurology International

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This study sought to ascertain the prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) among a sample of 465 patients with Long COVID. The participants completed three questionnaires: (1) a new questionnaire measuring both the frequency and severity of 38 common symptoms of COVID and Long COVID, (2) a validated short form questionnaire assessing ME/CFS, and (3) a validated questionnaire measuring post-exertional malaise. The population was predominantly white, female, and living in North America. The mean duration since the onset of COVID-19 symptoms was 70.5 weeks. Among the 465 participants, 58% met a ME/CFS case definition. Of respondents who reported that they had ME/CFS only 70.57% met criteria for ME/CFS and of those who did not report they had ME/CFS, 29.43% nevertheless did meet criteria for the disease: both over-diagnosis and under-diagnosis were evident on self-report. This study supports prior findings that ME/CFS occurs with high prevalence among those who have persistent COVID-19 symptoms.

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Comparing Operationalized Approaches for Substantial Reduction of Functioning in Chronic Fatigue Syndrome and Myalgic Encephalomyelitis

Cited by 2 publications

References 17 publications

Predictors of impaired functioning among long COVID patients

Predictors of impaired functioning among long COVID patients

ME/CFS and Post-Exertional Malaise among Patients with Long COVID

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