Comparing the Performance Status Scale and MD Anderson Dysphagia Inventory as swallowing outcome measures in head and neck cancer: a prospective cohort study

Khan, Muhammad; Patterson, Joanne; Owen, S; Rees, Siân Angharad; Gamberini, L; Paleri, V.

doi:10.1111/coa.12369

Cited by 9 publications

(6 citation statements)

References 22 publications

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“…Additionally, at all study occasions, the difference between the patients and the control group without dysphagia exceeded the suggested threshold (10 points) indicating a clinically important difference 15 . These results are in line with other studies of patients with HNC, where patients with oral and oropharyngeal tumors demonstrated similar values of the MDADI and with a similar pattern of change over time 12,19‐23 . Additionally, the a priori hypothesized correlations of changes over time of the MDADI domains to selected domains of the EORTC QLQ C30 and H&N35 were confirmed, where moderate correlations were found as expected, and with the strongest correlations to Social eating and Swallowing.…”

Section: Discussionsupporting

confidence: 89%

A longitudinal study of the Swedish MD Anderson Dysphagia Inventory in patients with oral cancer

Tuomi

Fransson

Wennerberg

et al. 2020

Laryngoscope Investig Oto

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Objective: The aim of this study was to investigate whether the Swedish MD. Anderson Dysphagia Inventory (MDADI) is able to detect changes in dysphagia symptoms over time for patients with head and neck cancer (HNC). Methods: One hundred and forty-two patients with resectable tumors of the oral cavity were included prior to treatment. The patients filled out the MDADI, European Organization for Research and Treatment of Cancer Quality of Life questionnaire Core 30 (EORTC QLQ-C30) and the HNC module (H&N35) at baseline and at least one follow-up at 6 and/or 12 months after oncologic treatment. A control group without dysphagia (n = 115) was included. Results: Self-perceived swallowing function decreased in all domains at 6 months, and improved between 6 and 12 months. The changes were similar to the changes of the EORTC domains, indicating a sensitivity to change. However, even if improvements were seen at 12 months, the values were still inferior compared to baseline values, and the values of a control group without dysphagia. Convergent validity was found with values of the MDADI and EORTC domains producing similar results, and moderate correlations as hypothesized. Patients with moderate-severe dysphagia according to the MDADI (<60 points) demonstrated inferior values of the EORTC domains compared to patients with scores above 60 points. Conclusion: The Swedish MDADI was found to be sensitive to change, and showed convergent results when compared to other established instruments. The threshold value for the MDADI (<60 points) indicating moderate-severe dysphagia may be a valuable addition in the clinical use.

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Section: Discussionsupporting

confidence: 89%

A longitudinal study of the Swedish MD Anderson Dysphagia Inventory in patients with oral cancer

Tuomi

Fransson

Wennerberg

et al. 2020

Laryngoscope Investig Oto

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“…In contrast, unlike previous studies that reported factors such as, age [16,18,19], marital status [46], and smoking [16][17][18] and deterioration in swallowing function through time [17,37,38], no associations were observed between age, smoking habit, marital status, time since diagnosis and type of carcinoma in this study.…”

Section: Discussioncontrasting

confidence: 99%

“…Factors predictive of poor quality of life (QoL) due to dysphagia could be patient-related [15] such as smoking [16][17][18], alcohol abuse [16], age [16,18,19], lean mass [16], and gender [16,19,20]; tumorrelated [15] such as advanced tumor stage [17,[21][22][23][24], location of HNC [25], such as patients with tongue [26], buccal [27], hypo pharyngeal [28] and laryngeal [29] tumors had worse dysphagia related QoL, type of treatment [15,25,30] in which higher level of dysphagia and lower QoL scores among patients who had radiotherapy [19], [31], [32], [29,33] and surgery [19,34,35] and patients treated with concomitant chemotherapy have an exacerbated dysphagia and dietary problems [36]. Deterioration in swallowing function through time were also reported from before treatment to 3 months [3,37,38] and 6 months [17,39] post treatment with some improvements at later times [17,37,38,…”

Section: Introductionmentioning

confidence: 99%

Dysphagia and Its Impact on Quality of Life of Head and Neck Cancer Patients: Institution Based Cross sectional Study

Yifru

Kısa

Dinegde

et al. 2020

Preprint

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Objective: Assessing swallowing function using symptom-specific questionnaires on head and neck cancer (HNC) patients and supporting impaired swallowing to improve quality of life (QoL) of patients is recommended in different studies. However, there is no data that shows the effect of dysphagia on quality of life of Ethiopian patients. Hence, this study assessed the effect of dysphagia on quality of life domains of the MD Anderson Dysphagia inventory (MDADI) among head and neck cancer patients.Results: The study sample consisted of mostly male (53.90%), employed (70.6%), single (57.80 %) and completed some level of formal education (66.60 %) with mean age of 42.58 years (SD ± 14.08 years) and medical expense for about 69.6% of patients was covered by the government. Most of the patients were suffering from advanced stage HNC (59.80%) and squamous cell carcinoma (62.70%) and the most prevalent tumor location was nasal cavity/ nasopharyngeal carcinoma (40.20%). The mean MDADI composite score was 53.29 (SD± 15.85). Being female, low income, suffering from laryngeal/ hypo pharyngeal cancer, suffering from advanced tumor and those undergoing a single modality therapy were key determinants of poor QoL related to swallowing problems in HNC patients.

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“…Our results were consistent with prior studies that identified the negative impact of cancer stage and location on swallowing related QoL. It is interesting to note that worse MDADI scores among patients with advanced tumor stages and had hypopharyngeal tumors observed in prior studies [10,23,24]. The literature results were consistent with the risk observed for lower QoL scores in our population.…”

Section: Discussionsupporting

confidence: 92%

“…The majority of patients in this study reported that their swallowing limits their daily activities. The composite MDADI mean scores in this study were considerably lower than reported in Brazil (63.36) [3,23,24], the USA (64.06 and 67) [10,23,24], and Taiwan (67.08) [25], indicating the severity of this problem in Ethiopia. The variation may be due to the fact that patients in Ethiopia lack access to early treatment and support since there is a single cancer center in the country that provides comprehensive cancer care.…”

Section: Discussioncontrasting

confidence: 73%

Dysphagia and its impact on the quality of life of head and neck cancer patients: institution-based cross-sectional study

et al. 2021

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Objective Impaired swallowing is a primary medical concern in head and neck cancer (HNC) patients. Swallowing therapy and supportive care to relieve swallowing problems among HNC patients are recommended. However, no data shows the effect of dysphagia on the quality of life (QoL) among Ethiopian patients. This cross-sectional study aimed to assess swallowing function and its impact on QoL. Results The sample included 102 HNC patients who visited oncology clinics at Tikur Anbessa Specialized Hospital. Majority were male (53.90%), employed (70.6%), single (57.80%), and completed some level of formal education (66.60%) with a mean age of 42.58 years (SD ± 14.08). More than half of the patients (69.6%) medical expenses were covered by the government. Most were suffering from advanced stage HNC (59.80%), squamous cell carcinoma (62.70%), and the most prevalent tumor location was nasopharynx (40.20%). The mean MDADI score was 53.29 (SD ± 15.85). Being female, low income, suffering from laryngeal cancer, advanced tumor, and undergoing a single modality therapy were crucial determinants of poor QoL related to swallowing problems. It is recommended to assess swallowing related QoL of patients using a validated tool and be included in treatment protocols.

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Comparing the Performance Status Scale and MD Anderson Dysphagia Inventory as swallowing outcome measures in head and neck cancer: a prospective cohort study

Abstract: This is the first prospective study comparing the MDADI and PSS questionnaires at multiple time points. Our study shows that these different instruments have a good relationship in measuring swallowing function in patients with head and neck cancer in short and medium term after treatment.

Cited by 9 publications

References 22 publications

A longitudinal study of the Swedish MD Anderson Dysphagia Inventory in patients with oral cancer

A longitudinal study of the Swedish MD Anderson Dysphagia Inventory in patients with oral cancer

Dysphagia and Its Impact on Quality of Life of Head and Neck Cancer Patients: Institution Based Cross sectional Study

Dysphagia and its impact on the quality of life of head and neck cancer patients: institution-based cross-sectional study

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