Comparison between conventional and intensity-modulated post-operative radiotherapy for stage III and IV oral cavity cancer in terms of treatment results and toxicity

Primary Tumor Site as a Predictor of Treatment Outcome for Definitive Radiotherapy of Advanced-Stage Oral Cavity Cancers

“…However, there is no observable difference between IMRT or non-IMRT treatments with regard to outcome. This conclusion is compatible with reports from other series (30). The radiation dose can achieve sufficient coverage in oral cavity cancer with two-or three-dimensional RT techniques because the lesions are relatively far away from critical organs, such as the spinal cord or the brainstem, compared with pharyngeal cancers, such as nasopharyngeal cancer or hypopharyngeal cancer.…”

Follow up after IMRT in oral cavity cancer: update

“…There is, so far, no evidence for superiority of IMRT compared to non-IMRT techniques with respect to OCC disease control [5,13]. Our small sample of patients with recurrent macroscopic disease referred for IMRT (n = 10/38) showed very poor outcome (LRC in 1/10, 8/10 died, Figures 1, 2), as also reported by Koo et al [9] and Schwartz et al [8].…”

Intensity-Modulated Radiotherapy for Oral Cavity Squamous Cell Carcinoma: Patterns of Failure and Predictors of Local Control

“…Prior clinical studies have suggested excellent outcomes for intensity-modulated RT (IMRT) when used in the head-and-neck region, usually in series dominated by oropharyngeal and nasopharyngeal cancers (6)(7)(8)(9)(10). Fewer studies have specifically evaluated IMRT for tumors of the OC (11)(12)(13)(14), in which target delineation is made more complicated by surgically distorted anatomy. We present a series of patients treated with IMRT for SCC of the OC with a focus on patterns of local-regional failure, issues related to timing of RT, and prognostic features of recurrence.…”