Comparison Between Purified Individual Tuberculoproteins and the International Standard Tuberculin*

Comparison between Tuberculoproteins A and C in the Serodiagnosis of Tuberculosis by Enzyme-Linked Immunosorbent Assay

“…This finding is comparable to studies conducted by Vandiviere et al [17]. They reported that the A-protein induced greater tuberculin skin reactions in humans as com pared to that of the C-protein.…”

“…They reported that the A-protein induced greater tuberculin skin reactions in humans as com pared to that of the C-protein. Using immunoelectrophoresis techniques, Daniel and Affronti [5] found that the A-protein with a molecular weight of 35,000-42,000 [17], contained antigen 1, 2, 5 and 6 and probably 4 when compared to the United StatesJapan tuberculin standard. Thus the greater potency manifested by the A-protein may be due to its large molecular weight and large number of antigens.…”

The Immunology of Mycobacterial Diseases1,2

“…Within the lymph nodes, lymphocytes become activated and release lymphokines, which initiate CM!. Lymphokines also activate monocytes from the blood, which report to sites of infection and mature into mac-(Received in original form October 24,1985 and in revised form December 13,1985) (18). Activated macrophages are felt to be a major factor in determining the outcome of infection with Mycobacterium (16).…”

New Aspects of Mycobacterial Skin Tests

“…The longest transverse diameter and the double skin-fold thickness was recorded so that the reaction could be caleulated as the segment of the volume of a sphere (V = 1/6 7T h(h2 + 3r 2 ); thus, data could be compiled and studied, based on the longest transverse diameterll or the volume. 13 Because of the "profile studies" already in the literature, these data are shown as longest transverse diameter.1s·1s…”