“…Unfortunately, these studies are also the most difficult to conduct, mainly due to the fact that in addition to your imaging findings you need to have clarity over the clinical signs as well as a confirmed outcome. At the moment the ‘gold standard’ for diagnosis is most commonly the post mortem examination, ideally including histopathology (although I do wonder if this is always true, especially in relation to MRI and scintigraphy that provide information about function rather than morphology which histopathology may not be able to show, see for example . Dr Sue Dyson and her group at the Animal Health Trust in Newmarket have conducted pioneering work in this area over recent decades and she has continued this with her paper in the current issue on the comparison between MRI and histological findings in the navicular bone in horses .…”