2014
DOI: 10.1590/jvb.2014.051
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Comparison between the conventional method and a portable device for determination of INR

Abstract: Context: Anticoagulation with warfarin is considered the appropriate treatment for venous thromboembolism and other thrombotic pathologies. Regular INR control is required for dosage adjustment and therapeutic control. Use of portable monitoring systems optimizes management of these patients. Objective: To compare INR measurements taken using the portable Coaguchek XS system in capillary blood with the standard laboratory method using venous blood. Method: Fifty-two samples each of venous and capillary blood w… Show more

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Cited by 7 publications
(6 citation statements)
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“…[9,10] Nevertheless, this study noted a drift in POCT in which INR was greater than or equal to 4.7, evoking caution regarding verifying the results by the core laboratory method under such conditions. This was also pointed out in a comparative Brazilian study [11] in 2014 wherein INR values of greater than 3.5 were confirmed by laboratory method instead of the Coaguchek XS system. Also, a Turkish study reported similar results with INR greater than 5.0.…”
Section: Discussionsupporting
confidence: 58%
“…[9,10] Nevertheless, this study noted a drift in POCT in which INR was greater than or equal to 4.7, evoking caution regarding verifying the results by the core laboratory method under such conditions. This was also pointed out in a comparative Brazilian study [11] in 2014 wherein INR values of greater than 3.5 were confirmed by laboratory method instead of the Coaguchek XS system. Also, a Turkish study reported similar results with INR greater than 5.0.…”
Section: Discussionsupporting
confidence: 58%
“…Therapeutic strategies complementary to statin use may be necessary for the management of dyslipidemia in t-PAPS patients, as statins may increase the risk of bleeding in patients taking anticoagulants [ 12 ]. A potential complementary therapy for dyslipidemia in PAPS is nutritional intervention with HD.…”
Section: Discussionmentioning
confidence: 99%
“…Statin therapy is the treatment of choice to control lipid levels and reduce cardiovascular morbidity. However, statin use may be challenging in APS patients with thrombosis since statins interact with vitamin K antagonists, the main anticoagulant drug used by these patients [ 4 , 11 ], increasing the risk of bleeding [ 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…The INR (International Normalized Index) test is used to evaluate blood coagulation, and is intended for the detection of disorders in this process, for therapeutic follow-up with anticoagulants, such as warfarin, and for the analysis of hemorrhagic risk and liver function (Araújo;Domingues;Van Bellen, 2014). In healthy individuals, normal INR values are between 0.8 and 1.0.…”
Section: International Normalised Ratio (Inr)mentioning
confidence: 99%