“…Many studies have shown that traditional NSAIDS (nonspecific) such as aspirin, indomethacin, and ibuprofen (our definition of NSAID does not include acetaminophen) impede bone healing in various animal models (see Table 1) [20,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48]. …”