Comparison Between the Kansas City Cardiomyopathy Questionnaire and New York Heart Association in Assessing Functional Capacity and Clinical Outcomes

Hawwa, Nael; Vest, Amanda R.; Kumar, Rahul; Lahoud, Rony; Young, James B.; Wu, Yuping; Gorodeski, Eiran Z.; Cho, Leslie

doi:10.1016/j.cardfail.2016.12.002

Cited by 26 publications

(29 citation statements)

References 17 publications

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“…All patients were administered the translated validated version of the Kansas City Cardiomyopathy Questionnaire (KCCQ) (CV Outcomes Inc) as a health status measure [ 5 , 8 ]. KCCQ is a patient-reported multidimensional instrument used in numerous studies since its introduction.…”

Section: Methodsmentioning

confidence: 99%

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Quality of life status determinants in hypertrophic cardiomyopathy as evaluated by the Kansas City Cardiomyopathy Questionnaire

Capota

Militaru

Ionescu

et al. 2020

Health Qual Life Outcomes

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Purpose The present study evaluated how heart failure (HF) negatively impacts health-related quality of life (HRQoL) in hypertrophic cardiomyopathy (HCM) patients and explored the major clinical determinants associated with HRQoL impairment in this population. Methods This was a cross-sectional single-center study of health-related HRQoL that included 91 consecutive patients with HCM. Evaluation was performed based on a comprehensive protocol that included the recommended diagnostic studies, as well as administration of the translated validated version of the Kansas City Cardiomyopathy Questionnaire (KCCQ) (CV Outcomes Inc) as a health status measure. Results The cohort included 52 (57%) males, median age 58 (20–85) years. The median global KCCQ score was 67 (12.5–100) corresponding to a moderate impairment in HRQoL. There was an inverse correlation between the median global KCCQ score and NYHA class (Kendall’s tau b coefficient r − 0.33, p = 0.001). Patients with pulmonary hypertension (PHT), defined as resting pulmonary artery systolic pressure of ≥ 45 mmHg, presented a significantly worse HRQoL as compared to those without PHT (median KCCQ score 56.2 vs 77.5, p = 0.013). The KCCQ score mildly correlated with age (r − 0.18, p = 0.014), history of syncope (r − 0.18, p = 0.045), estimated glomerular filtration rate (eGFR) (r 0.31, p < 0.001), plasmatic creatinine (r − 0.18, p = 0.017) and urea levels (r − 0.27, p < 0.001), left ventricular (LV) end-systolic dimensions (r − 0.18, p = 0.014), maximal provoked intraventricular gradient (r 0.20, p = 0.039), LV ejection fraction (r 0.15, p = 0.04), average E/e′ (r − 0.16, p = 0.039), pulmonary acceleration time (r 0.21, p = 0.007), pulmonary artery systolic pressure (r − 0.20, p = 0.016). In ordinal regression, the independent predictors of HRQoL were NYHA class and eGFR. Conclusions Patients with HCM and HF present a moderate degree of alteration in HRQoL. This is especially true for patients with PHT and more severe functional impairment. Renal failure and NYHA class are potential markers of HRQoL in clinical practice.

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Section: Methodsmentioning

confidence: 99%

“…KCCQ is a patient-reported multidimensional instrument used in numerous studies since its introduction. It is useful for estimating the perceived burden of heart failure symptoms [ 5 , 8 ]. The KCCQ is a self-administered questionnaire with scores ranging from 0 to 100, with higher values representing better HRQoL.…”

Section: Methodsmentioning

confidence: 99%

Quality of life status determinants in hypertrophic cardiomyopathy as evaluated by the Kansas City Cardiomyopathy Questionnaire

Capota

Militaru

Ionescu

et al. 2020

Health Qual Life Outcomes

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“…The 6‐Minute Walk Test is an objective measure of exercise capacity that can be used, and is especially effective in following patients over time . Other tools have been developed to better quantify the subjective effects of hypertrophic cardiomyopathy on quality of life such as the Kansas City Cardiomyopathy Questionnaire, which may be useful in this population as poor quality of life was cited as a strong factor in patients undergoing ASA in the current study . Finally, even a simple measurement of plasma natriuretic peptide (brain natriuretic peptide) has been shown to correlate with both NYHA Class and mortality in patients with HCM, and can be another useful tool in patients with questionable symptoms …”

Section: Introductionmentioning

confidence: 87%

How Symptomatic Should a Hypertrophic Obstructive Cardiomyopathy Patient Be to Consider Alcohol Septal Ablation?

Jones

Krishnaswamy

Smedira

et al. 2017

JAHA

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“…self-efficacy, quality of life, and social limitation) may add incremental value to NYHA classification. 19 The 6 min walk test is easy to implement, and it can give objective information about patient's exercise tolerance, especially in patients with severe symptoms, although it may not discriminate accurately HF severity among asymptomatic patients or those with mild symptoms. 20 The best method to assess functional capacity in HF patients is cardiopulmonary exercise stress test, as it provides accurate measures and prognostic parameters and may discriminate between cardiac and non-cardiac causes of exercise intolerance.…”

Section: Assessment Of Exercise Capacitymentioning

confidence: 99%

How to develop a national heart failure clinics network: a consensus document of the Hellenic Heart Failure Association

Filippatos¹,

Farmakis²,

Alexanian³

et al. 2020

ESC Heart Failure

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Heart failure (HF) is rapidly growing, conferring considerable mortality, morbidity, and costs. Dedicated HF clinics improve patient outcomes, and the development of a national HF clinics network aims at addressing this need at national level. Such a network should respect the existing health care infrastructures, and according to the capacities of hosting facilities, it can be organized into three levels. Establishing the continuous communication and interaction among the components of the network is crucial, while supportive actions that can enhance its efficiency include involvement of multidisciplinary health care professionals, use of structured HF‐specific documents, such as discharge notes, patient information leaflets, and patient booklets, and implementation of an HF‐specific electronic health care record and database platform.

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Comparison Between the Kansas City Cardiomyopathy Questionnaire and New York Heart Association in Assessing Functional Capacity and Clinical Outcomes

Cited by 26 publications

References 17 publications

Quality of life status determinants in hypertrophic cardiomyopathy as evaluated by the Kansas City Cardiomyopathy Questionnaire

Quality of life status determinants in hypertrophic cardiomyopathy as evaluated by the Kansas City Cardiomyopathy Questionnaire

How Symptomatic Should a Hypertrophic Obstructive Cardiomyopathy Patient Be to Consider Alcohol Septal Ablation?

How to develop a national heart failure clinics network: a consensus document of the Hellenic Heart Failure Association

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