Comparison between various biosensor methods for human T-lymphotropic virus-1 (HTLV-1) detection

Abstract

Due to the drawback of traditional and current diagnostic methods including serological and molecular assays, the development of the rapid and free-PCR techniques can be an alternative technique for the human T-cell lymphotropic virus (HTLV-1) DNA detection sequences. On the other hand, early detection of HTLV-1 prevents two dangerous diseases including Adult T-cell leukemia/lymphoma and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis. The biosensor-based methods are sensitive techniques that can provide new opportunities to detect infectious diseases, particularly in the early stage. This study provides a comparative view among recently designed biosensors for the detection of HTLV-1.

Advances in early diagnosis of cervical cancer based on biosensors

“…Biosensors can detect the biochemical markers of a disease, which can be found in different body fluids, such as urine, blood, or saliva. Biosensors can be classified according to the different types of biological components or type of physicochemical transduction (Kamali et al, 2021; Karunakaran et al, 2015; Zandi, Rasooli, et al, 2021). Based on the transducer, these systems can be classified into optical, piezoelectric, magnetic, and electrochemical biosensors; in addition, fluorescence‐based assays, electrochemical‐based assays, enzyme‐linked immunosorbent assays, and mass‐based detection are the current methods used for detecting tumor markers (Laraib et al, 2021; Mukhtar et al, 2021; Rocha‐Santos, 2014; Sargazi, Fatima, et al, 2022).…”