Comparison of 2-Dimensional and 3-Dimensional Conformal Treatment Plans in Gastric Cancer Radiotherapy

Abstract

Asian Pac J Cancer Prev, 15 (17), 7401-7405 IntroductionGastric cancer is the fourth common cancer worldwide and is the second leading cause of death from cancer (Qurieshi et al., 2011;Zare et al., 2013;Calik et al., 2014;Oh et al., 2014). At present complete resection is the only curative therapy (Yu et al., 2013). 25-40% of the patients are suitable for curative surgery. Postoperative local recurrence is an important issue; 38% loco regional recurrence and 28% peritoneal spread are observed post operatively (Czito et al., 2013). Intergroup 0116 study (INT 0116) demonstrated significance of post-operative RT in gastric cancer. Following a 10 year-follow-up period, a significant benefit was observed in relapse free survival and in overall survival (Smalley et al., 2012). Based on the results of this study, post-operative chemoradiotherapy became a standard procedure in stage IB-IV M0 patients. Because of the critical organs in the vicinity, which are low in tolerance, planning of RT in gastric cancer is important (Czito et al., 2013). In this study 2D and 3D therapy plannings were compared in terms of dosimetric parameters. The aim was to assess the field efficiency of the 2D plan and to evaluate the 3D plan in terms of both its coverage of the target volume and its effect to decrease the normal tissue doses.