Comparison of 2 vitamin D supplementation modalities in newborns: adherence and preference

Rodd, Celia; Jean-Philippe, Sonia; Vanstone, Catherine A.; Weiler, Hope A.

doi:10.1139/h11-018

Cited by 23 publications

(18 citation statements)

References 11 publications

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“…Interestingly 80% of caregivers reported giving their infants D-Drops ® versus only 16% who supplemented with D-Vi-Sol ® . The reason for the popularity of D-Drops ® may be their ease of administration requiring only a single drop that can be placed on the mother's breast prior to nursing, versus the need to use a dropper to administer D-Vi-Sol ® [25]. …”

Section: Discussionmentioning

confidence: 99%

Very high vitamin D supplementation rates among infants aged 2 months in Vancouver and Richmond, British Columbia, Canada

Crocker

Green²,

Barr³

et al. 2011

BMC Public Health

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BackgroundVitamin D deficiency during infancy may lead to rickets and possibly other poor health outcomes. The World Health Organization recommends exclusive breastfeeding for the first 6 months. Breast milk is the best food for infants but does not contain adequate vitamin D. Health Canada recommends all breastfed infants receive a daily vitamin D supplement of 400 IU; however, there appears to be limited current Canadian data as to whether parents or caregivers are following this advice. The aim of this study was to determine the rates of vitamin D supplementation among 2-month old infants in Vancouver and Richmond, British Columbia, Canada.MethodsMothers of all healthy infants born between April and May 2010 were approached to participate. Telephone surveys were conducted with 577 mothers (response rate 56%) when their infants turned 2 months.ResultsOver half of the infants received only breast milk in the week prior to the survey. One third received a mixture of breast milk and infant formula and 10% received only formula. About 80% of the infants were supplemented with vitamin D at 2 months. Infants who received only breast milk were most likely to be supplemented with vitamin D (91%). Over 60% of the infants had a total vitamin D intake of 300- < 500 IU/d from supplements and formula and only 5% did not receive any vitamin D. Most parents were advised to give vitamin D supplement by health professionals, such as public health nurses, midwives, and doctors.ConclusionsAbout 90% of the infants received breast milk at 2 months of age. The vitamin D supplementation rate was 80%. Future studies are needed to monitor breastfeeding duration and vitamin D supplementation rates as infants get older.

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Section: Discussionmentioning

confidence: 99%

Very high vitamin D supplementation rates among infants aged 2 months in Vancouver and Richmond, British Columbia, Canada

Crocker

Green²,

Barr³

et al. 2011

BMC Public Health

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“…Despite the simplicity of the prevention and treatment of vitamin D deficiency, many studies have confirmed poor patient treatment adherence, more so in preventative strategies ( Rodd et al, 2011 ; Grant et al, 2014 ). The option of stoss therapy or single large dose vitamin D treatment to combat the problems associated with treatment adherence has been recommended.…”

Section: Treatment Of Nutritional Ricketsmentioning

confidence: 99%

The roles of vitamin D and dietary calcium in nutritional rickets

Thandrayen

Pettifor

2018

Bone Reports

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The etiology and pathogenesis of nutritional rickets are becoming progressively clearer. Vitamin D deficiency has generally been considered the major or only player in the pathogenesis of nutritional rickets. However, recent research into calcium deficiency has now provided clinicians with reasons to investigate and manage patients with nutritional rickets more appropriately.The important question when assessing cases of nutritional rickets is: “Is it calcium or vitamin D deficiency or both that play a major role in the pathogenesis of the disease?”The case presentation in this review highlights the risk factors, clinical presentation and pathophysiology of nutritional rickets in a young South African black child from a semi-urban area in Johannesburg, a city with abundant sunshine throughout the year.

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“…Options include fortification of additional foods, which is very effective and inexpensive (27), or Stoss therapy with large dose oral or intramuscular doses of vitamin D, which remains controversial in paediatrics (1). Ongoing campaigns to alert communities to risks of deficiency and the importance of supplements will be vital; promotion of easy to use preparations has improved uptake in Canada (28). There are lessons to be learned from Turkey and the city of Birmingham, that have implemented successful and inexpensive programs through ongoing education by all health care providers at every visit or patient contact (29,30).…”

Section: Discussionmentioning

confidence: 99%

A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg

Lautatzis

Sharma

Rodd

2018

Paediatrics &Amp; Child Health

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Objectives: Vitamin D deficiency rickets remains a problem in Canada. Our primary objective was to determine the annual incidence of rickets and/or early vitamin D deficiency in Manitoba. Secondarily, we investigated if there was an increase in the annual incidence. Methods: A retrospective chart review was undertaken to identify cases in our catchment area from 2003 to 2015. Data sources included endocrine and hospital charts and radiology reports. Early vitamin D deficiency was determined by review of all 25(OH)D tests from 2011 to 2015. Values less than 30 nmol/L with an elevated bone marker prompted a chart review in children under 7 years. Results: We identified 46 cases of rickets and 68 with early vitamin D deficiency. For Manitoba, the annual incidence of rickets was 8.2 cases per 100,000 in infants, and 1.6 per 100,000 in children aged 1 to 7 years. Those with early vitamin D deficiency had annual incidences of 2.7 per 100,000 infants and 9.9 per 100,000 Manitoban children. No temporal trends were noted for either. For both disorders, most cases were from northern or rural locales; about 50% were of self-declared Indigenous or Inuit heritage, and the majority (>75%) of children were from families with high material deprivation using area-based socioeconomic measures. Conclusion: Despite several decades of preventative efforts, the incidence of rickets was comparable to previous Canadian reports, particularly in infants. Greater education across the lifespan and engagement with communities and public health agencies will be needed to reduce the high incidence of this preventable disease.

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Comparison of 2 vitamin D supplementation modalities in newborns: adherence and preference

Cited by 23 publications

References 11 publications

Very high vitamin D supplementation rates among infants aged 2 months in Vancouver and Richmond, British Columbia, Canada

Very high vitamin D supplementation rates among infants aged 2 months in Vancouver and Richmond, British Columbia, Canada

The roles of vitamin D and dietary calcium in nutritional rickets

A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg

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