Comparison of 3D CRT and IMRT Tratment Plans

Bakiu, Erjona; Telhaj, Ervis; Kozma, E.; Ruçi, Ferdinand; Malkaj, P.

doi:10.5455/aim.2013.21.211-212

Cited by 28 publications

(12 citation statements)

References 7 publications

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“…Radiotherapy aims to deliver sufficient dose to the tumor target and spare the organ at risk (OAR) around target to achieve the goal, that is, killing the tumor cell with minimum toxicity to the normal tissues. Advanced irradiation techniques such as intensity modulated radiotherapy (IMRT) [ 1 ], volumetric modulated arc therapy (VMAT) [ 2 ], and stereotactic radiation therapy (SRT) [ 3 ] can generate complex dose distribution with high dose areas firmly conformed to the target. Because of the high dose gradients at the boundary of target, the anatomical change due to weight loss, tumor shrinkage, and growth during the treatment will lead to inaccurate dose delivered to patient with respect to the initial planning.…”

Section: Introductionmentioning

confidence: 99%

A Method to Improve Electron Density Measurement of Cone-Beam CT Using Dual Energy Technique

Men

Dai

et al. 2015

BioMed Research International

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Purpose. To develop a dual energy imaging method to improve the accuracy of electron density measurement with a cone-beam CT (CBCT) device. Materials and Methods. The imaging system is the XVI CBCT system on Elekta Synergy linac. Projection data were acquired with the high and low energy X-ray, respectively, to set up a basis material decomposition model. Virtual phantom simulation and phantoms experiments were carried out for quantitative evaluation of the method. Phantoms were also scanned twice with the high and low energy X-ray, respectively. The data were decomposed into projections of the two basis material coefficients according to the model set up earlier. The two sets of decomposed projections were used to reconstruct CBCT images of the basis material coefficients. Then, the images of electron densities were calculated with these CBCT images. Results. The difference between the calculated and theoretical values was within 2% and the correlation coefficient of them was about 1.0. The dual energy imaging method obtained more accurate electron density values and reduced the beam hardening artifacts obviously. Conclusion. A novel dual energy CBCT imaging method to calculate the electron densities was developed. It can acquire more accurate values and provide a platform potentially for dose calculation.

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Section: Introductionmentioning

confidence: 99%

A Method to Improve Electron Density Measurement of Cone-Beam CT Using Dual Energy Technique

Men

Dai

et al. 2015

BioMed Research International

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“…Radiotherapy aims to give the prescribed dose to the tumor and to protect as much as possible to organs at risk and surrounded healthy tissue. The radiotherapy nowadays, together with chemotherapy and surgery, is a way to treat the patients who have different kind of tumors [1].…”

Section: Introductionmentioning

confidence: 99%

Influence of Dosimetric Considerations in Evaluating Second Cancer Risks in Prostate Cancer

Elgendy¹,

Attia²,

Attalla³

et al. 2018

IJMPCERO

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Influence of dosimetric considerations in evaluating second cancer risks in prostate cancer. Material and methods: Fifteen patients in this study suffering from early stage of prostate cancer, each patient underwent three plans: 1) Three-dimensional conformal radiation therapy (3DCRT), 2) Rotation therapy (Arc therapy), and 3) intensity-modulated radiation therapy (IMRT) plan. Estimate secondary metastasis risk models: Excess Relative Risk (ERR) and Excess absolute risk (EAR) based on age of exposure by taking dosimetry data from Dose Volume Histograms (DVHs) to calculate risk models. Result: The second cancer risk models (ERR and EAR) for organs at risk OARs decrease with increasing age of exposure for 3D-CRT, ARC and IMRT and there is no significant difference for ERR and EAR model for developing second cancer risk in 3D-CRT, ARC and IMRT.

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“…Radiation therapy, along with chemotherapy and surgery, plays an important role in the treatment of head and neck tumors. The most common purpose of radiotherapy is to deliver a therapeutic dose to the tumor without damaging the surrounding tissues [3,4]. The radiotherapy process begins by performing a patient's scan.…”

Section: Introductionmentioning

confidence: 99%

“…Finally, the patient plan that has been produced by the physicist using treatment planning system (TPS) is transferred to the treatment machine. The importance of all these processes are to ensure accurate treatment of the patient by a proper treatment plan [4]. Over the past two decades, in order to reduce the complications of radiotherapy and increase the therapeutic efficacy, treatment planning techniques have been significantly improved.…”

Section: Introductionmentioning

confidence: 99%

“…Radiation damage to the spinal cord can cause paralysis, numbness, and impairment in the function and control of the bladder and intestine [11,12]. According to the articles, in order to reduce secondary complications, the highest tolerable spinal cord dose is 45-50 Gy [4,13]. Loss of speech and voice quality and laryngeal edema is due to unnecessary laryngeal radiation during treatment of head and neck tumors [14].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors

Pour

Farajollahi

Jamali³

et al. 2018

Polish Journal of Medical Physics and Engineering

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Introduction: Due to the effect of radiation on both the tumor and the surrounding normal tissues, the side effects of radiation in normal tissues are expected. One of the important complications in the head and neck radiotherapy is the doses reached to the larynx and spinal cord of patients with non-laryngeal head and neck tumors.Materials and Methods: In this study, CT scan images of 25 patients with non-laryngeal tumors including; lymph nodes, tongue, oropharynx and nasopharynx were used. A three-field and a four-field treatment planning with and without laryngeal shield in 3D CRT technique were planned for each patient. Subsequently, the values of Dmin, Dmean, Dmax and Dose Volume Histogram from the treatment planning system and NTCP values of spinal cord and larynx were calculated with BIOPLAN and MATLAB software for all patients.Results: Statistical results showed that mean values of doses of larynx in both three and four-field methods were significantly different between with and without shield groups. Comparison of absorbed dose didn’t show any difference between the three and four field methods (P>0.05). Using Shield, just the mean and minimum doses of spinal cord decreased in both three and four fields. The NTCP of the spinal cord and larynx by three and four-field methods with shield in the LKB and EUD models significantly are less than that of the three and four fields without shields, and in the four-field method NTCP of larynx is less than three radiation field.Conclusion: The results of this study indicate that there is no significant difference in doses reached to larynx and spinal cord between the treatments techniques, but laryngeal shield reduce dose and NTCP values in larynx considerably.

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Comparison of 3D CRT and IMRT Tratment Plans

Cited by 28 publications

References 7 publications

A Method to Improve Electron Density Measurement of Cone-Beam CT Using Dual Energy Technique

A Method to Improve Electron Density Measurement of Cone-Beam CT Using Dual Energy Technique

Influence of Dosimetric Considerations in Evaluating Second Cancer Risks in Prostate Cancer

Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors

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