Comparison of 4% articaine and 0.5% levobupivacaine/2% lidocaine mixture for sub-Tenon's anaesthesia in phacoemulsification cataract surgery: a randomised controlled trial

Raman, Sundaresan; Barry, John-S; Murjaneh, S; Jacob, J; Quinn, Anthony G.; Sturrock, G. D.; Shaw, Steven M.; Allman, Keith G.

doi:10.1136/bjo.2007.115576

Cited by 16 publications

(7 citation statements)

References 12 publications

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“…There appears to be no clinically significant difference between lidocaine and articaine when used for spinal [38, 39], epidural [40] or brachial plexus regional anaesthesia [41]. Articaine provides superior akinesia and a more rapid onset of anaesthesia than a lidocaine and bupivacaine mixture when used in a sub‐Tenon’s block for cataract surgery [42, 43]. As the majority of the studies involving articaine had a small number of participants (with the exception of studies of dental surgery), it is difficult to recommend its use in preference to lidocaine, especially as concerns exist relating to its potential for neurotoxicity [44].…”

Section: Developments In Local Anaesthetic Agentsmentioning

confidence: 99%

Local anaesthetics and adjuvants – future developments

Wiles¹,

Nathanson²

2010

Anaesthesia

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Summary The introduction of local anaesthesia some years after the first public demonstration of general anaesthesia not surprisingly created less excitement and interest amongst both the public and the medical profession. However, in its own way, a new revolution was happening. Local anaesthesia produced an increase in the choice of anaesthetic techniques available to practitioners and patients. In common with general anaesthesia, the choice of agents remained very limited for the first six decades, and interest in the practice of local, regional or central neuraxial blockade and the development of new techniques and drugs were hampered by perceived safety issues even as late as the second half of the 20th century. It is only in the last few years that, with an apparent renaissance in the use of local anaesthesia, the pace of development has picked up. As the use and range of techniques has increased, so has interest in solving some of the longstanding problems with the available drugs.

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Section: Developments In Local Anaesthetic Agentsmentioning

confidence: 99%

Local anaesthetics and adjuvants – future developments

Wiles¹,

Nathanson²

2010

Anaesthesia

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“…In another study, articaine 4% was found to be safer and superior than a mixture of lidocaine 2% and levobupivacaine 0.5% in achieving ocular akinesia for sub-Tenon's block in phacoemulsification cataract surgery. 12 In our practice, we prefer to use articaine in septoplasty surgery for LA considering its proven efficacy and safety in a range of clinical settings.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Local Anesthesia with Articaine and Lidocaine in Septoplasty Procedure

Erkul

Babayiğit

Kuduban

2010

Am J Rhinol�Allergy

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“…Up to 5 mL of articaine was injected until the first sign of conjunctival chemosis appeared, causing a reduction in ocular movement and readiness for surgery in 3.5 minutes (SD 2.5); one failure was reported. In a comparable randomized controlled trial, 4 mL articaine 4% in all but one of the 31 patients was enough 62. None of the patients in the articaine groups developed any clinically significant ocular motility problems following surgery 59–62…”

Section: Therapeutic Efficacymentioning

confidence: 95%

“…In a comparable randomized controlled trial, 4 mL articaine 4% in all but one of the 31 patients was enough 62. None of the patients in the articaine groups developed any clinically significant ocular motility problems following surgery 59–62…”

Section: Therapeutic Efficacymentioning

confidence: 95%

Articaine: a review of its use for local and regional anesthesia

Snoeck¹

2012

LRA

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Articaine is an intermediate-potency, short-acting amide local anesthetic with a fast metabolism due to an ester group in its structure. It is effective with local infiltration or peripheral nerve block in dentistry, when administered as a spinal, epidural, ocular, or regional nerve block, or when injected intravenously for regional anesthesia. In comparative trials, its clinical effects were not generally significantly different from those of other short-acting local anesthetics like lidocaine, prilocaine, and chloroprocaine, and there is no conclusive evidence demonstrating above-average neurotoxicity. Articaine proved to be suitable and safe for procedures requiring a short duration of action in which a fast onset of anesthesia is desired, eg, dental procedures and ambulatory spinal anesthesia, in normal and in special populations.

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Comparison of 4% articaine and 0.5% levobupivacaine/2% lidocaine mixture for sub-Tenon's anaesthesia in phacoemulsification cataract surgery: a randomised controlled trial

Abstract: Articaine (4%) is a safer and a superior anaesthetic agent than a mixture of 2% lidocaine and 0.5% levobupicaine in achieving ocular akinesia for sub-Tenon's block in phacoemulsification cataract surgery.

Cited by 16 publications

References 12 publications

Local anaesthetics and adjuvants – future developments

Local anaesthetics and adjuvants – future developments

Comparison of Local Anesthesia with Articaine and Lidocaine in Septoplasty Procedure

Articaine: a review of its use for local and regional anesthesia

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