2012
DOI: 10.1016/j.tripleo.2011.04.037
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Comparison of 4% articaine with epinephrine (1:100,000) and without epinephrine in inferior alveolar block for tooth extraction: double-blind randomized clinical trial of anesthetic efficacy

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Cited by 41 publications
(40 citation statements)
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“…[1112] Surprisingly, it has been observed that patients receiving 4% articaine with 1:100,000 epinephrine, had a significantly earlier onset of anesthetic effect as compared to 4% plain articaine (7.2 minutes vs. 9.2 minutes; P =.001) Even the duration of soft tissue anesthesia has been observed to be significantly longer in patients receiving 4% articaine with epinephrine as compared to 4% plain articaine (3.8 hours vs. 2.5 hours; P <.0001). [13]…”
Section: Pharmacologymentioning
confidence: 99%
See 1 more Smart Citation
“…[1112] Surprisingly, it has been observed that patients receiving 4% articaine with 1:100,000 epinephrine, had a significantly earlier onset of anesthetic effect as compared to 4% plain articaine (7.2 minutes vs. 9.2 minutes; P =.001) Even the duration of soft tissue anesthesia has been observed to be significantly longer in patients receiving 4% articaine with epinephrine as compared to 4% plain articaine (3.8 hours vs. 2.5 hours; P <.0001). [13]…”
Section: Pharmacologymentioning
confidence: 99%
“…[29] Hypotension occurred early and more frequently with articaine. [13] Since lignocaine has a high incidence of neurotoxicity, articaine may be an alternative for short acting (ambulatory) spinal anesthesia. However, the potential for neurotoxicity with articaine is yet not completely known.…”
Section: Pharmacologymentioning
confidence: 99%
“…Dessa forma, questionários buscando verificar os impactos das condições ou doenças especificas têm sido cada vez mais descritos por atribuírem uma melhor capacidade discriminatória aos problemas pontuais e, portanto, permitirem uma leitura mais fidedigna da condição e suas repercussões sobre o indivíduo [1][2][3][4][5][6][7][8] . Todavia, a maioria dos estudos relacionados à cirurgia bucal tende a quantificar e descrever os impactos, as consequências, os resultados e os desconfortos das terapias empregadas somente no pós-procedimento e, quando o transoperatório é avaliado, em geral a dor é o único item de interesse 9 . Genericamente, o cirurgião-dentista realiza os procedimentos cirúrgicos e de extração dentária de rotina atento à técnica e, em geral, objetivando a reabilitação.…”
Section: Introductionunclassified
“…Both the central nervous system and the cardiovascular system are particularly sensitive to high plasma concentrations of local anesthetics. In addition, epinephrine as adjunct has an additional influence on cardiovascular function [2,3] like changes in heart rate, blood pressure, and cardiac dysrhythmia [4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%