Comparison of 5-Item and 11-Item Modified Frailty Index as Predictors of Functional Independence in Patients With Spinal Cord Injury

Mouchtouris, Nikolaos; Luck, Trevor; Locke, Katherine; Hines, Kevin; Franco, Daniel; Yudkoff, Clifford; Sivaganesan, Ahilan; Heller, Joshua; Prasad, Srinivas; Harrop, James; Jack Jallo,

doi:10.1177/21925682231211279

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…12 Recently the ACS-NSQIP switched to the 5-item modified Frailty index (mFI-5), which has shown efficacy in predicting postsurgical outcomes. [12][13][14][15] This study aims to compare the demographic characteristics, types of surgery, and postsurgical complications of patients 90 years of age and older undergoing elective otolaryngology surgeries to a younger geriatric cohort, utilizing the ACS-NSQIP database. We hypothesize that age alone does not significantly influence elective surgical outcomes in nonagenarians and centenarians and that frailty defined by the mFI-5 is a better predictor in this age group.…”

Section: Introductionmentioning

confidence: 99%

Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology–Head and Neck Surgery: A NSQIP Study

Srinivasan,

Briano,

Czaja

et al. 2024

The Laryngoscope

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ObjectiveTo describe types and outcomes of elective otolaryngological surgeries undergone by patients ≥90 years of age and to assess whether very old age is an independent risk factor for postsurgical complications and death.MethodsThe National Surgical Quality Improvement Program, a validated national prospective surgical outcomes database, was used to identify all patients aged 65 years and older who underwent elective otolaryngological procedures from 2011 to 2020. Study outcomes included minor complications, major life‐threatening complications, and 30‐day mortality. Predictors of outcomes, including frailty, were identified using univariable analyses and age was added into the final logistic regression models with stepwise selection.ResultsA total of 40,723 patients met inclusion criteria; 629 (1.5%) patients were ≥90 years of age. Of the 63,389 procedures, head and neck (67.6%) and facial plastics and reconstructive (15.0%) procedures were most common. The overall incidence of major life‐threatening complications, minor complications, and death was 2.0%, 3.5%, and 0.4%, respectively. Age ≥90 was significantly associated with an increased risk for 30‐day mortality, but not with major or minor postoperative complications. A high modified frailty index was significantly associated with an increased risk for major postoperative complications and death amongst patients ≥90 years.ConclusionsElective otolaryngological surgery can be safe in relatively healthy nonagenarians and centenarians, though there is a small increased risk of 30‐day mortality. Although older age can predispose patients to other comorbidities, age alone should not deter surgeons and patients from considering elective otolaryngological procedures. Frailty may be a better predictor for surgical outcomes.Level of EvidenceLevel IV Laryngoscope, 2024

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Section: Introductionmentioning

confidence: 99%

Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology–Head and Neck Surgery: A NSQIP Study

Srinivasan,

Briano,

Czaja

et al. 2024

The Laryngoscope

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Impact of frailty on survival glioblastoma, IDH-wildtype patients

Hudelist,

Elia,

Roux

et al. 2024

J Neurooncol

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The prognostic significance of modified frailty index-5 in patients undergoing pneumonectomy for lung cancer

Sayan,

Artiran,

Ozturk

et al. 2024

Interdisciplinary CardioVascular and Thoracic Surgery

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OBJECTIVES In some centrally located lung cancers, complete excision of the mass cannot be achieved with parenchymal sparing procedures, and pneumonectomy may be required. The mortality and morbidity rates of pneumonectomy were reported considerably high. Here, we investigated the effectivity of modified frailty index-5 (MFI-5) in patients undergoing pneumonectomy for non-small cell lung cancer (NSCLC). METHODS Data of patients who underwent pneumonectomy for NSCLC between January 2018 and December 2023 were reviewed retrospectively. MFI-5 score was determined by preoperative diabetes mellitus, hypertension, chronic obstructive pulmonary diseases, congestive heart failure, and functional status. The effectiveness of the MFI-5 score for the presence of postoperative major complications and 30-day mortality was investigated by multivariate logistic regression analysis. A p-value less than 0.05 was considered statistically significant. RESULTS A total of 107 patients who met the inclusion criteria were included in the study. Eight (7,5%) of patients were female, and the mean age was 61,4 ± 8,7. MFI-5 score was 0 in 48 patients (44.9%), 1 in 27 patients (25.2%), and 2 in 20 patients (18.7%). Postoperative 30-day mortality was detected in 4 patients (3,7%), and the major complications occurred in 42 patients (39,3%). In multivariate analysis, an MFI-5 score of 2 or higher (p = 0,008, OR: 4,9) was statistically significant for complications, whereas age, gender, side of operation, less than 2 MFI-5 score, tumour diameter, type of surgery, and lymph node metastasis status were not statistically significant (p > 0,05). CONCLUSIONS The MFI-5 score is a significant indicator for predicting major postoperative events in patients who underwent pneumonectomy for NSCLC.

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Comparison of 5-Item and 11-Item Modified Frailty Index as Predictors of Functional Independence in Patients With Spinal Cord Injury

Cited by 4 publications

References 26 publications

Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology–Head and Neck Surgery: A NSQIP Study

Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology–Head and Neck Surgery: A NSQIP Study

Impact of frailty on survival glioblastoma, IDH-wildtype patients

The prognostic significance of modified frailty index-5 in patients undergoing pneumonectomy for lung cancer

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