Comparison of a 1.5T Standard vs. 3T Optimized Protocols in Multiple Sclerosis Patients (P03.053)

Livshits, Ilya; Hussein, Sara; Kennedy, Cheryl; Weinstock‐Guttman, Bianca; Hojnacki, David; Zivadinov, Robert

doi:10.1212/wnl.78.1_meetingabstracts.p03.053

Cited by 4 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…7T could improve radiological correlations with neurological disability as increased field strength provides greater sensitivity to lesions. 22,23 Potentially correlations at lower field strengths are hampered by insensitivity to lesions as suggested in Figure 4. Further tests are needed to compare SC lesion identification in multiple scanning planes across field strengths but our data suggests a substantial improvement in lesion conspicuity at 7T.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T

et al. 2015

View full text Add to dashboard Cite

Background The clinical course of MS is mainly attributable to cervical and upper thoracic spinal cord dysfunction. High-resolution, 7T anatomical imaging of the cervical spinal cord is presented. Image contrast between gray/white matter and lesions surpasses conventional, clinical T1- and T2-weighted sequences at lower field strengths. Objective To study the spinal cord of healthy controls and patients with MS using magnetic resonance imaging at 7T. Methods Axial (C2-C5) T1- and T2*-weighted and sagittal T2*-/spin-density-weighted images were acquired at 7T in 13 healthy volunteers (age 22-40 years), and 15 clinically diagnosed MS patients (age 19-53 years, EDSS 0-3) in addition to clinical 3T scans. In healthy volunteers, a high-resolution multi-echo gradient echo scan was obtained over the same geometry at both fields. Evaluation included signal and contrast to noise ratios and lesion counts for healthy and patient volunteers, respectively. Results/Conclusion High-resolution images at 7T exceeded resolutions reported at lower field strengths. Gray and white matter were sharply demarcated and MS lesions were more readily visualized at 7T compared to clinical acquisitions. with lesions apparent at both fields. Nerve roots were clearly visualized. White matter lesion counts averaged 4.7 vs. 3.1 (52% increase) per patient at 7T vs. 3T, respectively (p = 0.05).

show abstract

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The fMRI BOLD 3 Tesla (3T) measurements section of the study highlights the advantages of using 3T MRI over the standard 1.5T, including superior resolution, reduced scan time, and increased sensitivity, particularly beneficial for motor function and somatosensory processing tasks [16][17][18]. The study involved two fMRI sessions on a healthy, normosmic female subject without comorbidities to assess the feasibility of data processing, safety, and the absence of brain alterations that could skew results.…”

Section: Fmri Bold 3 Tesla Measurementsmentioning

confidence: 99%

Olfactory Rehabilitation for Chronic Pain: A Multi-Dimensional Approach Supported by fMRI Insights

Santantonio,

Riso,

Gaudino

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…В то же время применение современных КВ при РС в рекомендованной дозе (0,1 ммоль/кг) зачастую не эффективно, а повышение дозы ведет к увеличению частоты возникновения побочных эффектов [11]. Для решения этой проблемы применяют различные методы [12] и режимы сканирования [13][14][15][16][17][18][19], а также разрабатывают новые КВ (высокорелаксивные хе-латы гадолиния, наночастицы оксида железа, макромолекулярные конъюгаты, векторные препараты), способные с более высокой чувствительностью визуализировать патологические очаги при РС и повышать точность диагностического заключения [20,21].…”

Section: методы исследования и диагностикиunclassified

Contrast agents in MRI-diagnosis of multiple sclerosis

Abakumova

Nukolova

Gusev

et al. 2015

Z. nevrol. psikhiatr. im. S.S. Korsakova

View full text Add to dashboard Cite

Magnetic resonance imaging using contrast agents plays an important role in diagnosis and assessment of treatment efficacy in multiple sclerosis. The development of contrast agents on the basis of gadolinium or iron oxide nanoparticles has potential for diagnosis of pathological foci (tumors, amyloid plaques, inflammation and foci of demyelination or necrosis) in nervous system diseases. Newly developing types of diagnostic substances for visualization of pathological foci in multiple sclerosis are presented in this review.

show abstract

Comparison of a 1.5T Standard vs. 3T Optimized Protocols in Multiple Sclerosis Patients (P03.053)

Cited by 4 publications

References 0 publications

Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T

Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis at 7T

Olfactory Rehabilitation for Chronic Pain: A Multi-Dimensional Approach Supported by fMRI Insights

Contrast agents in MRI-diagnosis of multiple sclerosis

Contact Info

Product

Resources

About