“…15,16 Ling 17 showed empiric treatment to be effective in low-risk patients, including women aged 18 to 45 years with regular menses, no previous diagnosis of endometriosis, no hormonal treatment in the prior 3 months, no evidence of gastrointestinal or urinary disease, normal pelvic ultrasound, normal complete blood count, normal urinalysis, negative gonorrhea and chlamydia culture, negative human chorionic gonadotropin, and failure of NSAIDs and doxycycline to improve pain symptoms (SORT B). Of patients treated empirically, 80% experienced significant improvement, including patients without detectable endometriosis at subsequent laparoscopy.…”