Comparison of a lightweight polypropylene mesh (Optilene® LP) and a large-pore knitted PTFE mesh (GORE® INFINIT® mesh)—Biocompatibility in a standardized endoscopic extraperitoneal hernia model

Jacob, Dietmar; Schug-Paß, C.; Sommerer, Florian; Tannapfel, Andrea; Lippert, H.; Köckerling, F.

doi:10.1007/s00423-011-0858-8

Cited by 20 publications

(11 citation statements)

References 45 publications

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“…In this meta-analysis, there were no cases of mesh removal for the reason of infection in cases treated with the sublay technique. This may be because of the lower rate of inflammatory reaction and better defense against infection with large-pore lightweight mesh [ 43 ]. After preparation of the bowel and the management of pollution, mesh can be used in the presence of open bowel with minimal risk of infection [ 44 , 45 ].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Prophylactic Mesh in End‐Colostomy Construction: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Wang

Zhu

et al. 2016

World j. surg.

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BackgroundParastomal hernia is a very common complication after colostomy, especially end-colostomy. It is unclear whether prophylactic placement of mesh at the time of stoma formation could prevent parastomal hernia formation after surgery for rectal cancer. A systematic review and meta-analysis were conducted to evaluate the efficacy of prophylactic mesh in end-colostomy construction.MethodsPubMed, Embase, and the Cochrane Library were searched, covering records entered from their inception to September 2015. Randomized controlled trials (RCTs) comparing stoma with mesh to stoma without mesh after surgery for rectal cancer were included. The primary outcome was the incidence of parastomal hernia. Pooled risk ratios (RR) with 95 % confidence intervals (CI) were obtained using random effects models.ResultsSix RCTs containing 309 patients were included. Parastomal hernia occurred in 24.4 % (38 of 156) of patients with mesh and 50.3 % (77 of 153) of patients without mesh. Meta-analysis showed a lower incidence of parastomal hernia (RR, 0.42; 95 % CI 0.22–0.82) and reoperation related to parastomal hernia (RR, 0.23; 95 % CI 0.06–0.89) in patients with mesh. Stoma-related morbidity was similar between mesh group and non-mesh group (RR, 0.65; 95 % CI 0.33–1.30).ConclusionsProphylactic placement of a mesh at the time of a stoma formation seems to be associated with a significant reduction in the incidence of parastomal hernia and reoperation related to parastomal hernia after surgery for rectal cancer, but not the rate of stoma-related morbidity. However, the results should be interpreted with caution because of the heterogeneity among the studies.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Prophylactic Mesh in End‐Colostomy Construction: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Wang

Zhu

et al. 2016

World j. surg.

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“…The idea pursued was adequate host tissue incorporation to improve the strength of the repair zone putting this mesh in competition with the lightweight and heavyweight PP prostheses. Experimental findings have indicated no difference in tissue incorporation in relation to conventional PP mesh [ 47 , 48 ].…”

Section: Classic Polymer Biomaterials and Hernia Repairmentioning

confidence: 99%

Polymer Hernia Repair Materials: Adapting to Patient Needs and Surgical Techniques

et al. 2021

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Biomaterials and their applications are perhaps among the most dynamic areas of research within the field of biomedicine. Any advance in this topic translates to an improved quality of life for recipient patients. One application of a biomaterial is the repair of an abdominal wall defect whether congenital or acquired. In the great majority of cases requiring surgery, the defect takes the form of a hernia. Over the past few years, biomaterials designed with this purpose in mind have been gradually evolving in parallel with new developments in the different surgical techniques. In consequence, the classic polymer prosthetic materials have been the starting point for structural modifications or new prototypes that have always strived to accommodate patients’ needs. This evolving process has pursued both improvements in the wound repair process depending on the implant interface in the host and in the material’s mechanical properties at the repair site. This last factor is important considering that this site—the abdominal wall—is a dynamic structure subjected to considerable mechanical demands. This review aims to provide a narrative overview of the different biomaterials that have been gradually introduced over the years, along with their modifications as new surgical techniques have unfolded.

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“…One of the most common prosthetics used in clinical practice is the Optilene ® lightweight PP mesh. This mesh was compared with a large-pore knitted polytetrafluoroethylene (PTFE) mesh and both meshes showed comparable biocompatibility regarding chronic inflammatory reaction [116]. Its good tissue integration and good tissue adhesion characteristics ,make PP meshes suitable for hernia repair surgery.…”

Section: 1non-bioabsorbable Meshesmentioning

confidence: 99%

Prosthetic Meshes for Hernia Repair: State of Art, Classification, Antimicrobial Approaches, and Fabrication Methods

Serrano‐Aroca¹,

Pous‐Serrano²

2021

Preprint

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Worldwide, hernia repair represents one of the most frequent surgical procedures encompassing a global market valued at several billion dollars. This type of surgery usually requires the implantation of a mesh that needs the appropriate chemical, physical and biological properties for the type of repair. This review thus presents a description of the types of hernias, current hernia repair methods, and the state of the art of prosthetic meshes for hernia repair providing the most important meshes used in clinical practice by surgeons working in this area classified according to their biological or chemical nature, morphology and whether bioabsorbable or not. We emphasise the importance of surgical site infection in herniatology, how to deal with this microbial problem, and we go further into the future research lines on the production of advanced antimicrobial meshes to improve hernia repair and prevent microbial infections, including multidrug-resistant strains. A great deal of progress has been made in this biomedical field in the last decade. However, we are still far from an ideal antimicrobial mesh that can also provide excellent integration to the abdominal wall, mechanical performance, low visceral adhesion and minimal inflammatory or foreign body reactions, among many other problems.

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Comparison of a lightweight polypropylene mesh (Optilene® LP) and a large-pore knitted PTFE mesh (GORE® INFINIT® mesh)—Biocompatibility in a standardized endoscopic extraperitoneal hernia model

Cited by 20 publications

References 45 publications

Efficacy of Prophylactic Mesh in End‐Colostomy Construction: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Efficacy of Prophylactic Mesh in End‐Colostomy Construction: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Polymer Hernia Repair Materials: Adapting to Patient Needs and Surgical Techniques

Prosthetic Meshes for Hernia Repair: State of Art, Classification, Antimicrobial Approaches, and Fabrication Methods

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