Comparison of a self‐administered tampon ThinPrep test with conventional pap smears for cervical cytology

Budge, Mardi; Halford, J. A.; Haran, Mano; Mein, Jacki; Wright, Gordon

doi:10.1111/j.1479-828x.2005.00392.x

Cited by 15 publications

(16 citation statements)

References 8 publications

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“…Our findings are consistent with the larger body of research on acceptability of vaginal and/or cervical selfsampling devices [47,53,60] utilized in clinical and community settings. In a clinical setting, Budge et al [53] assessed women's acceptability of a tampon-based collection method for cytology and found that acceptability was very high (91.2%) compared to standard Pap smears (45.8%).…”

Section: Discussionsupporting

confidence: 94%

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Assessing the acceptability of self-sampling for HPV among Haitian immigrant women: CBPR in action

Barbee

Kobetz

Menard

et al. 2009

Cancer Causes Control

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When paired with CHWs, who are of Haitian descent and well respected in Little Haiti, self-sampling is a highly acceptable method of cervical screening for Haitian women in this ethnic enclave. This approach addresses critical access barriers, including poverty, language difficulties, and sociocultural concerns about modesty, that may similarly affect Pap smear utilization among other immigrant or medically underserved population sub-groups. Coupled with generally positive reviews of the device, the low rate of insufficient specimens for testing suggests that this device is promising for use in non-clinical settings.

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Section: Discussionsupporting

confidence: 94%

“…Cervical self-sampling has previously been demonstrated to be an acceptable alternative to the Pap smear domestically and abroad [46,[50][51][52][53]. However, our study is the first to our knowledge to examine the acceptability of this approach for Haitian immigrant women living in the United States.…”

Section: Discussionmentioning

confidence: 73%

Assessing the acceptability of self-sampling for HPV among Haitian immigrant women: CBPR in action

Barbee

Kobetz

Menard

et al. 2009

Cancer Causes Control

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“…The accuracy of self-collected Papanicolaou smears is unproven, with variations in accuracy depending on the technique employed. 5,6 However, self-sampling for the human papillomavirus is emerging as an accurate and effective technique for cervical cancer screening through a variety of methods. [7][8][9][10] Although self-sampling research has been more focused on developing countries where access to providers is limited, self-sampling techniques that avoid speculum insertion deserve further consideration for all populations as alternatives that, in addition to being potentially less traumatic, may also increase screening rates.…”

Section: Discussionmentioning

confidence: 99%

Genitourinary Infections after a Routine Pelvic Exam

Tiemstra

Chico²,

Pela³

2011

The Journal of the American Board of Family Medicine

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Purpose: To determine if genitourinary problems are more common in women in the first 1 to 2 months after a routine pelvic examination.Methods: This was a historical cohort study in 2 family medicine teaching clinics at an urban university. Participants included all women who received a Papanicolaou smear during calendar year 2006. Subjects included all participants for weeks 1 to 7 after their Papanicolaou smear. Controls were all participants in weeks 8 to 52 after their Papanicolaou smear. The independent variable was time after Papanicolaou smear, and dependent variables included frequency of visits for urinary complaints, diagnosed urinary tract infections (UTIs), vaginal complaints, diagnosed vaginitis, and sexually transmitted diseases. Relative frequencies compared using 2-tailed t tests.Results: UTIs and urinary complaints were significantly more frequent during the first 7 weeks after a Papanicolaou smear compared with weeks 8 to 14, 8 to 48, and 8 to 52. The overall rate of UTIs was 7.33 per 100 person-years; the attributable risk during the first 7 weeks was 0.82 per 100 personyears, or 11% of observed UTIs. Combined Candidal and bacterial vaginitis was marginally more frequent during the first 7 weeks compared with weeks 8 to 48 and 8 to 52 only. The incidence of sexually transmitted diseases combined was 1.13 per 100 person-years, distributed evenly over the study period unrelated to time. Urinary tract infections (UTIs) are very common among adult women, accounting for more than 6 million physician office visits yearly in the United States. Sexual intercourse has long been recognized as one of the primary risk factors for female UTIs. 1Proposed mechanisms for this increased risk include propulsion of bacteria up the urethra into the bladder; microtrauma to the urethra and bladder mucosa, allowing bacterial adhesion; and alteration of normal flora. We postulated that the pelvic examination, including speculum insertion and bimanual examination, may increase the risk of UTIs by similar mechanisms. A small, retrospective, casecontrol study suggested such an association.2 A recent study has also demonstrated that symptoms of UTIs, namely dysuria and frequency, are more common in sexually active women in the 4 weeks after a screening pelvic examination.3 This study examined a larger cohort of women after a routine pelvic examination for the timing and frequency of genitourinary problems. MethodsThis was a historical cohort study performed by chart review. Participants were all women who had a Papanicolaou test at either of our 2 clinics during the calendar year 2006. Participants were identified through billing records, and a total of 1582 women were included. Participants were excluded only if they had no follow-up visit at our medical center since the initial Papanicolaou smear. The 2 clinics are university-based family medicine clinics in an urban setting, serving a diverse, large-city popula-

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“…However, repeat testing is inevitably associated with loss to follow-up, which has been shown to be as high as 28-33% [39,40]. Furthermore, it has been shown that Pap cytology cannot be reliably performed on self-sampled material [52][53][54][55]. Another general limitation is the suboptimal sensitivity of Pap cytology for cancers: even after the preselection of hrHPVpositive women, not all cervical carcinomas are detected [24,56].…”

Section: Pap Cytologymentioning

confidence: 99%

Management of high-risk HPV-positive women for detection of cervical (pre)cancer

Luttmer

Strooper

Steenbergen

et al. 2016

Expert Review of Molecular Diagnostics

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Introduction: Primary HPV-testing has been shown to provide a superior detection of women at risk of cervical (pre)cancer compared to cytology-based screening. However, as most high-risk HPV infections are harmless, additional triage testing of HPV-positive women is necessary to identify those with cervical (pre)cancer. In this paper, we compare the performance, advantages and limitations of clinically relevant available triage strategies for HPV-positive women. Areas covered: Many different colposcopy triage strategies, comprising both microscopy-based and molecular (virus/host-related) markers, have been suggested: Pap cytology, p16/Ki-67 dual-stained cytology, HPV16/18 genotyping, viral DNA methylation and host cell DNA methylation. Literature search was limited to triage strategies that have achieved at least phase 2 of the five-phase framework for biomarker development and studies including large cohorts (≥100 hrHPV-positive women). Triage markers were stratified by sample type (cervical scrape, self-collected sample) and by study population (screening, non-attendee, referral). Expert commentary: At present, repeat Pap cytology and Pap cytology combined with HPV16/18 genotyping are the only triage strategies that have been robustly shown to be ready for implementation. Other strategies such as p16/Ki-67 dual-stained cytology and host cell DNA methylation analysis, with or without additional HPV16/18 genotyping, are attractive options for the near future. ARTICLE HISTORY

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Comparison of a self‐administered tampon ThinPrep test with conventional pap smears for cervical cytology

Cited by 15 publications

References 8 publications

Assessing the acceptability of self-sampling for HPV among Haitian immigrant women: CBPR in action

Assessing the acceptability of self-sampling for HPV among Haitian immigrant women: CBPR in action

Genitourinary Infections after a Routine Pelvic Exam

Management of high-risk HPV-positive women for detection of cervical (pre)cancer

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