Comparison of A-type Proanthocyanidins in Cranberry and Peanut Skin Extracts Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

Ye, Liyun; Neilson, Andrew P.; Sarnoski, Paul J.; Ray, W. Keith; Duncan, Susan E.; Boyer, Renee Raiden; O’Keefe, Sean F.

doi:10.4172/1747-0862.1000209

Cited by 6 publications

(6 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 Estimated from analysis of raw extract by mass spectrophotometer and HPLC methods. 4 Molecular weights estimated from Ye et al [39]. 5 Estimated from analysis of raw extract by the Folin-Ciocalteu method, not by direct analysis of the drinks.…”

Section: Methodsmentioning

confidence: 99%

Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies

Prpa

Corpe

Atkinson

et al. 2020

The Journal of Nutritional Biochemistry

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies

Prpa

Corpe

Atkinson

et al. 2020

The Journal of Nutritional Biochemistry

View full text Add to dashboard Cite

show abstract

“…Fruits were extracted as described by Ye et al (2016), with slight modifications. Briefly, 100 mL of a solution containing acetone : 2% CH 3 COOH in water (70 : 30, v/v) was added to 30 g cranberries; the mixture was blended in a Waring blender and extracted for 10 min in an ultrasonic water bath.…”

Section: Cranberry Fruit Extractionmentioning

confidence: 99%

Identification of markers for the authentication of cranberry extract and cranberry-based food supplements

Gardana

Scialpi²,

Fachechi³

et al. 2020

Heliyon

View full text Add to dashboard Cite

Due to the high cost of the cranberry extract, there have been several reported cases of adulteration. The aim of our study was to find markers to authenticate extracts or cranberry-based food supplements. Cranberry fruits from 7 countries, 17 cranberry extracts and 10 cranberry-based food supplements were analysed by UPLC-DAD-Orbitrap MS. Procyanidins were assessed by DMAC method. Anthocyanin fingerprint and epicatechin/catechin, procyanidin A2/total procyanidin and procyanidin/anthocyanin ratios were used as markers, and PCA carried out to check for similarity. Approximately 24% and 60% of the extracts and food supplements, respectively, differed significantly from the fruits. One seemed adulterated with Morus nigra and two with Hibiscus extract. Six food supplements were non-compliant and five contained mainly cyanidin-glucoside and cyanidin-rutinoside, suggesting adulteration with M. nigra extract. Only four products contained the procyanidin amount declared on the package, and only one provided the daily dose deemed effective for treating a urinary tract infection.

show abstract

“…In another example, consumption of cranberries (high in type A procyanidins) is recommended to help prevent urinary tract infections since they prevent the attachment of the bacteria to the lining of the urinary tract (Nicolosi, Temperam, Genovese, & Furneri, ). Cranberries have a similar concentration of type A procyanidin as peanut skins (Ye et al., ).…”

Section: Discussionmentioning

confidence: 99%

“…PSE was prepared from crude peanut skins donated by Seabrook Ingredients (Edenton, NC). Extraction methodology followed previously published methods (Adamson et al., ; Robbins et al., ; Ye et al., ) with slight modification. Briefly, 50 g peanut skins were shaken in a sieve to remove dust and combined with 750 ml hexane, mixed thoroughly, and sonicated for 10 min.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of peanut skin and grape seed extracts to inhibit growth of foodborne pathogens

Levy

Boyer

Neilson

et al. 2017

Food Science & Nutrition

View full text Add to dashboard Cite

Peanut skin extract (PSE) and grape seed extract (GSE) are derived from waste products in the wine and peanut industries, respectively. Both have high concentrations of polyphenols, known to possess antioxidant and antimicrobial properties. PSE primarily contains “A‐type” procyanidins, while GSE primarily contains “B‐type” procyanidins. These differ structurally, but are both isomers of epicatechin dimers. The objective of this study was to evaluate the antimicrobial effects of PSE containing A‐type procyanidins and GSE containing B‐type procyanidins against select foodborne pathogens (Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella Typhimurium). The minimum inhibitory concentration (MIC) of the two extracts on L. monocytogenes, E. coli O157:H7, and S. Typhimurium was determined using the pour plate method. GSE had a significantly lower MIC (p ≤ .05) than PSE for L. monocytogenes (GSE = 60.6 ppm, PSE > 68.2 ppm) and S. Typhimurium (GSE = 45.7 ppm, PSE = 60.6 ppm), but no difference in inhibition of E. coli O157:H7. Since GSE contributed to greater inhibition, GSE extract was fractionated into monomer‐rich (consisting primarily of catechins, epicatechins, and epicatechin gallates) and oligomer‐rich (consisting of dimers, trimers, tetramers, up to decamers) components. Growth curves of all three pathogens in the presence of full extract, monomer and oligomer fractions were compared separately. None of the extracts inhibited S. Typhimurium growth. Generally, the extract containing greater oligomer components inhibited growth of L. monocytogenes and E. coli O157:H7 when compared to the control. Results indicate that an extract with type B procyanidins higher in oligomers may have greater antimicrobial properties.

show abstract

Comparison of A-type Proanthocyanidins in Cranberry and Peanut Skin Extracts Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

Cited by 6 publications

References 18 publications

Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies

Apple polyphenol-rich drinks dose-dependently decrease early-phase postprandial glucose concentrations following a high-carbohydrate meal: a randomized controlled trial in healthy adults and in vitro studies

Identification of markers for the authentication of cranberry extract and cranberry-based food supplements

Evaluation of peanut skin and grape seed extracts to inhibit growth of foodborne pathogens

Contact Info

Product

Resources

About