Comparison of Albumin/Globulin (A/G) Ratio Between Pregnant and Lactation of Thin-Tail Sheep

Abstract

The albumin/globulin (A/G) ratio can be an immunological indicator of sheep which can be influenced by reproductive status such as pregnant and lactation conditions. However, a study of A/G ratio during pregnant and lactation in thin-tailed sheep is still lack. This study aimed to determine the levels of A/G ratio in thin-tailed sheep during pregnancy and lactation. This study used twelve of ewes thin-tailed sheeps (seven pregnant sheeps, and five lactating sheeps) rearing in Berbah, Sleman, Yogyakarta. Blood samples were collected through the jugular vein and filled into the EDTA tube and then albumin and total protein were measured. The levels of globulin were calculated by subtracting the total protein with albumin. The mean of A/G ratio in pregnant and lactation thin-tailed sheep was 0.72±0.18, and 0.57±0.15, respectively. Statistical analysis showed that there was no significantly difference in A/G ratio between pregnant and lactation (P>0.05). In conclusion, the difference in physiological status (pregnancy versus lactation) had no significant effect on the A/G ratio in thin-tailed sheep.

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“…Albumin (ALB) and globulin (GLB) are two major components of total proteins in serum, which play an important role in inflammation, and are measured using commercial kits (Nanjing Jiancheng Bioengineering Institute). The albumin/globulin (A/G) is a biochemical parameter that is used to interpret changes in serum proteins that accompany the chronic disease, with A/G ratios calculated to assess potential alterations in inflammatory responses …”

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