Comparison of antibacterial property of herbal plant–based bio-active extract loaded polymer electrospun nanofibrous mat wound dressings

Abstract

Treating wound is challenging if there is microbial colonization. In this paper, we tried to review comparison of bacterial inhibition zone of different herbal plant bioactive loaded polymer electrospun nanofibrous wound dressings. A systematic literature search called preferred reporting items for systematic reviews and meta-analyses (PRISMA) was used to review bacterial inhibition zone of the different herbal plant bioactive loaded polymer electrospun nanofibrous mats used for wound dressing applications. The literatures were searched from PubMed, Scopus, Web of Science, and Google Scholar databases published in English from 2010 to 2021. Two hundred articles were searched out; from these, 93 articles are selected and studied their bacterial inhibition zone, among them eight have the highest bacterial inhibition zone greater than or equal to 20 mm. From the studied plant bioactive extract loaded polymer electrospun nanofibrous mat wound dressings, PVA/ Tridax procumbensviz have the highest antibacterial property (42 mm and 35 mm bacterial inhibition zone to Staphylococcus aureus and Escherichia coli, respectively). The second highest antibacterial property is PVA /honey/Curcuma longa with bacterial inhibition zone of 38 mm to S. aureus and the third one is PCL/carboxyethyl chitosan/PVA/ Matricaria chamomile L. with an inhibition zone of 37.5 mm to E. coli bacteria.

Analysis and comparison of bioactive phytochemical composition and antibacterial property of two Ethiopian indigenous medicinal plants

“…Traditional Chinese medicine, for example, has been used comparably to allopathic medicine for the diagnosis, treatment, and prevention of illness for over 2,000 years. [1][2][3] In our previous review article, [4,5] we explained that the main reason delayed wound healing is the presence of wound infection, which often occurs due to various pathogens such as Escherichia coli (E. coli), Salmonella typhi (S. typhi), and Staphylococcus aureus (S. aureus), is the major reason for delayed wound healing. Notably, E. coli and S. aureus have been identified as being the most predominant bacteria responsible for severe wound infection.…”

“…Notably, E. coli and S. aureus have been identified as being the most predominant bacteria responsible for severe wound infection. [4] Therefore, incorporating the antibacterial agents into wound dressings will prevent infection of wound against these pathogens. Antimicrobials such as antibiotics, synthetic nanoparticles, like zinc oxide and sliver nanoparticles, have antibacterial effects; however, most of nanoparticles and synthetic antibiotics have some disadvantages, such as toxicity, environment impact, health risks, bacteria resistance issues, and very expensive that developing countries cannot afford.…”

“…Consequently, natural antibacterial from natural materials (having inheritance medicinal properties) with their advantage of non-toxicity or fewer side effect, environmental friendliness, availability, and low cost are becoming the new research area. [4] In developing countries, wounds are major problems managed alternatively through using traditional medicinal plants which are abundant, affordable, effective and safe. [6] Today, the discovery of new antibacterial based on natural products is an incredibly important goal and still one of the major sources of new drug molecules.…”

“…In our previous review article, [4,5] we explained that the main reason delayed wound healing is the presence of wound infection, which often occurs due to various pathogens such as Escherichia coli ( E. coli ), Salmonella typhi ( S. typhi ), and Staphylococcus aureus (S. aureus), is the major reason for delayed wound healing. Notably, E. coli and S. aureus have been identified as being the most predominant bacteria responsible for severe wound infection [4] . Therefore, incorporating the antibacterial agents into wound dressings will prevent infection of wound against these pathogens.…”

“…Antimicrobials such as antibiotics, synthetic nanoparticles, like zinc oxide and sliver nanoparticles, have antibacterial effects; however, most of nanoparticles and synthetic antibiotics have some disadvantages, such as toxicity, environment impact, health risks, bacteria resistance issues, and very expensive that developing countries cannot afford. Consequently, natural antibacterial from natural materials (having inheritance medicinal properties) with their advantage of non‐toxicity or fewer side effect, environmental friendliness, availability, and low cost are becoming the new research area [4] . In developing countries, wounds are major problems managed alternatively through using traditional medicinal plants which are abundant, affordable, effective and safe [6] …”