Comparison of Appropriate Piperacillin/Tazobactam Doses in Korean Obese Patients with Cancer Based on Different Body Size Descriptor Equations in a Tertiary Care Hospital

Abstract

Piperacillin/tazobactam (TZP) is a broad-spectrum antibiotic with coverage against gram-positive, gram-negative, and aerobic/ anaerobic organisms, and is used principally to treat pneumonia, peritonitis, febrile neutropenia, and intra-abdominal infection, as well as for prophylactic treatment. 1-3) TZP has reliable activity against Pseudomonas aeruginosa, which is resistant to multiple antibiotics; therefore, it plays an important role in treating patients with serious infections and preventing the development of resistant organisms. 4-7) According to the Infectious Diseases Society of America (IDSA) and National Comprehensive