2023
DOI: 10.3390/biomedicines11082229
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Comparison of Autografts and Biodegradable 3D-Printed Composite Scaffolds with Osteoconductive Properties for Tissue Regeneration in Bone Tuberculosis

Abstract: Tuberculosis remains one of the major health problems worldwide. Besides the lungs, tuberculosis affects other organs, including bones and joints. In the case of bone tuberculosis, current treatment protocols include necrectomy in combination with conventional anti-tuberculosis therapy, followed by reconstruction of the resulting bone defects. In this study, we compared autografting and implantation with a biodegradable composite scaffold for bone-defect regeneration in a tuberculosis rabbit model. Porous thre… Show more

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Cited by 2 publications
(1 citation statement)
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“…Further advancements have emerged as other authors [ 178 ] introduced 3D-printed composite scaffolds comprised of poly(ε-caprolactone) (PCL) infused with nanocrystalline cellulose and poly (γ-glutamic acid) (PGlu), serving as implants for bone regeneration in rabbit femur bones. The composites, combined with adhered rabbit bone mesenchymal stem cells (MSCs), showed an osteo-regeneration effect.…”
Section: Pharmaceutical Applications Of Cellulose-based Textilesmentioning
confidence: 99%
“…Further advancements have emerged as other authors [ 178 ] introduced 3D-printed composite scaffolds comprised of poly(ε-caprolactone) (PCL) infused with nanocrystalline cellulose and poly (γ-glutamic acid) (PGlu), serving as implants for bone regeneration in rabbit femur bones. The composites, combined with adhered rabbit bone mesenchymal stem cells (MSCs), showed an osteo-regeneration effect.…”
Section: Pharmaceutical Applications Of Cellulose-based Textilesmentioning
confidence: 99%