Comparison of Bone Mineral Density and Area of Newly Formed Bone Around Ti-15%Zr-4%Nb-4%Ta Alloy and Ti-6%Al-4%V Alloy Implants

Numata, Yoshihiro; Tanaka, Sakae; Okazaki, Yoshimitsu; Tanimoto, Yasuhiro; Tamaki, Hiroyuki; Katou, Takao; Ookubo, Atsushi; Kobayashi, Kihei; LeGeros, Racquel Z.

doi:10.2485/jhtb.17.99

Cited by 11 publications

(4 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Measurements can be taken without pretreatment or advanced skills, and the technique is particularly useful for bone density measurements and microstructural analyses of bone tissues. This modality is commonly used in other fields of research [26][27][28] ; in this study, we found that the technique was able to clarify differences in bone microarchitecture among rats subject to oestrogen deficiency, and combined oestrogen-mineral deficiency.…”

Section: D Bone Density Distribution Mapsmentioning

confidence: 56%

Quantitative and Qualitative Analyses of Low-mineral-diet Ovariectomised Rat Femora Using Microscopic Computed Tomography

Suzuki¹,

Tanaka²,

Tanimoto³

et al. 2011

J. Hard Tissue Biology.

Self Cite

View full text Add to dashboard Cite

The aim of this study was to monitor changes in bone density and bone quality (microarchitecture) in the femoral epiphyseal region in rats with bone loss induced by oestrogen deficiency and accelerated by mineral deficiency. Forty-eight Wistar rats were divided into 3 groups (n = 16 per group): Group 1, sham-operated rats on a normal diet; Group 2, ovariectomised rats on a normal diet; and Group 3, ovariectomised rats on a mineraldeficient diet. Observations were conducted 4, 8, 16, and 24 weeks after the operation (sham or ovariectomy), while the rats were on their respective diets. Microscopic computed tomography of the femoral epiphyseal region was used to generate 3-dimensional bone density distribution maps, and to compute bone density values. Densities of cortical and cancellous bone in Groups 2 and 3 were significantly less than densities in Group 1, and densities in Group 3 were significantly less than densities in Group 2 at nearly every post-operative time interval.This study demonstrated that: a) ovariectomy in rats induces bone loss; b) a mineral-deficient diet accelerates bone loss that has been induced by oestrogen deficiency; and c) 3-dimensional bone density distribution maps may be useful in diagnosing osteoporosis and other diseases causing bone loss. Microscopic computed tomography is a powerful analytical tool for measuring spatial variations in bone density, and temporal changes in the patterns of 3-dimensional bone density distribution maps.

show abstract

Section: D Bone Density Distribution Mapsmentioning

confidence: 56%

Quantitative and Qualitative Analyses of Low-mineral-diet Ovariectomised Rat Femora Using Microscopic Computed Tomography

Suzuki¹,

Tanaka²,

Tanimoto³

et al. 2011

J. Hard Tissue Biology.

Self Cite

View full text Add to dashboard Cite

show abstract

“…5) o reabsorción ósea en el hueso cercano al biomaterial implantado (Kuroda et al 1998). Nakada et al (2008) propone el empleo de las aleaciones de titanio de la familia TNTZ para ser empleadas en implantes ortopédicos. Esta familia de aleaciones presenta un bajo módulo elástico, excelente resistencia mecánica, elevada resistencia a la corrosión y están compuestas por elementos biocompatibles.…”

Section: Resistencia Mecánicaunclassified

Desarrollo de aleaciones de titanio: implicaciones en el sector biomédico europeo

Femenia¹,

Amigó²

2023

View full text Add to dashboard Cite

Esta monografía se orienta a explorar los conceptos relacionados con la fabricación de aleaciones avanzadas de titanio, que permitan satisfacer los requisitos en servicio necesarios para ser empleados como prótesis. Se estructura en cinco capítulos donde se abordará la problemática industrial del desarrollo de aleaciones avanzadas de titanio. En el primer capítulo se expone la situación actual de las aleaciones de titanio dentro del sector médico. En el segundo capítulo se examinan las tecnologías empleadas para la fabricación de aleaciones. En el tercer capítulo se abordan los conceptos de modificación superficial. En el cuarto capítulo, se identifican las vías y etapas para eliminar la porosidad residual. El último capítulo evalúa el efecto que tiene la composición química, la microestructura y el tratamiento superficial en la resistencia frente a la corrosión de las aleaciones de titanio.

show abstract

“…Studies in rabbit animal models showed that fracture in tibia reported lowest bone atrophy and hence better bone remodelling for TNTZ rods and plates as compared to Ti-6Al-4V ELI, and SUS 316L. The diameter of the tibia was increased, and a double wall structure was observed for intramedullary bone when TNTZ were used as rods [60][61][62][63][64][65].…”

Section: Alloys and Coatings Of Tantalum Ti-29nb-13ta-46zr (Tntz)mentioning

confidence: 99%

Tantalum as a Novel Biomaterial for Bone Implant: A Literature Review

Putrantyo

Anilbhai

Vanjani

et al. 2021

JBBBE

View full text Add to dashboard Cite

Titanium (Ti) has been used in metallic implants since the 1950s due to various biocompatible and mechanical properties. However, due to its high Young’s modulus, it has been modified over the years in order to produce a better biomaterial. Tantalum (Ta) has recently emerged as a new potential biomaterial for bone and dental implants. It has been reported to have better corrosion resistance and osteo-regenerative properties as compared to Ti alloys which are most widely used in the bone-implant industry. Currently, Tantalum cannot be widely used yet due to its limited availability, high melting point, and high-cost production. This review paper discusses various manufacturing methods of Tantalum alloys, including conventional and additive manufacturing and also discusses their drawbacks and shortcomings. Recent research includes surface modification of various metals using Tantalum coatings in order to combine bulk material properties of different materials and the porous surface properties of Tantalum. Design modification also plays a crucial role in controlling bulk properties. The porous design does provide a lower density, wider surface area, and more immense specific strength. In addition to improved mechanical properties, a porous design could also escalate the material's biological and permeability properties. With current advancement in additive manufacturing technology, difficulties in processing Tantalum could be resolved. Therefore, Tantalum should be considered as a serious candidate material for future bone and dental implants.

show abstract

Comparison of Bone Mineral Density and Area of Newly Formed Bone Around Ti-15%Zr-4%Nb-4%Ta Alloy and Ti-6%Al-4%V Alloy Implants

Cited by 11 publications

References 29 publications

Quantitative and Qualitative Analyses of Low-mineral-diet Ovariectomised Rat Femora Using Microscopic Computed Tomography

Quantitative and Qualitative Analyses of Low-mineral-diet Ovariectomised Rat Femora Using Microscopic Computed Tomography

Desarrollo de aleaciones de titanio: implicaciones en el sector biomédico europeo

Tantalum as a Novel Biomaterial for Bone Implant: A Literature Review

Contact Info

Product

Resources

About