1997
DOI: 10.1097/00004728-199711000-00003
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Comparison of Cerebral Blood Volume Measurements Using the T1 and T2* Methods in Normal Human Brains and Brain Tumors

Abstract: Both methods are able to determine rCBV in routine clinical studies. If the goal is to obtain quick, qualitative multislice information, the T2* method is adequate. For quantitative evaluations, however, the T1 method should be preferred.

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Cited by 42 publications
(44 citation statements)
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“…In theory, it can be determined from Eq. [27] with a signal measured in the lumen of the artery, but this is not practically feasible due to the small size of the arteries in the brain. A corrected expression for R 1,A can be found by applying the principles leading to Eq.…”
Section: Dce-mri Signal and Partial Volume Correctionmentioning
confidence: 99%
See 2 more Smart Citations
“…In theory, it can be determined from Eq. [27] with a signal measured in the lumen of the artery, but this is not practically feasible due to the small size of the arteries in the brain. A corrected expression for R 1,A can be found by applying the principles leading to Eq.…”
Section: Dce-mri Signal and Partial Volume Correctionmentioning
confidence: 99%
“…The change in tissue relaxation rate R 1 was calculated for every voxel with Eq. [27]. R 10,B was taken from the R 10 -value in the venous voxel and R 1,A was calculated with Eq.…”
Section: Postprocessingmentioning
confidence: 99%
See 1 more Smart Citation
“…Alternatively, simultaneous T1 and T2* data collection techniques can be used (Barbier et al, 1999;Zhu et al, 2000;d'Arcy et al, 2002). Recently, T1 measurements combined with modelling methods have been developed for estimating brain blood volume and permeability based on first-pass kinetics (Hacklander et al, 1996(Hacklander et al, , 1997Ludemann et al, 2001;Johnson et al, 2004). Roberts et al (2000) have described a slow time resolution technique for estimating blood volume and permeability in the brain.…”
Section: Secondary End Points From Dce-mrimentioning
confidence: 99%
“…The dynamic methods, including the Dynamic Susceptibility Contrast method (Moonen et al, 1992;Rosen et al, 1991;Villringer et al, 1988) and the T 1 bolus method (Dean et al, 1992;Hacklander et al, 1996Hacklander et al, , 1997, are based on the intravascular indicator dilution theory (Meier and Zierler, 1954) and require high temporal resolution to acquire series of images during the first pass of the bolus of the injected tracer in the brain tissue. The area under the curve describing the temporal change of the relaxation rate DR 1 = (DT 1 ) À1 or DR 2 * = (DT 2 *) À1 during bolus passsage has been demonstrated to be proportional to the CBV (Belliveau et al, 1990;Hacklander et al, 1996).…”
Section: Introductionmentioning
confidence: 99%