Comparison of chemical composition and biological activities of Seseli rigidum fruit essential oils from Serbia

Abstract

Abstract:Plants from genus Seseli, have been widely used in European traditional medicine, exhibiting antibacterial, antifungal, insect repellent, emmenogogue, antiflatulence, anti-inflammatory, antinociceptive, anti-tumor, antirheumatic activities and protective effect on human lymphocytes DNA. They usually grow on mountain rocky terrains. Part of their habitat on Vidlic Mountain, located in South-east Serbia, was struck with a large wildfire. Seseli rigidum fruit essential oils (from post fire and control areas) compositions were analyzed by GC and GC-MS, identifying monoterpenes α-pinene and sabinene as most abundant. Statistical tests showed a non-significant difference in chemical composition of these two oils, but a significant difference in comparison with the herb from a geographically different origin. Antimicrobial tests showed strong activities of the oils against tested bacteria, thus confirming its administration in various inflammation processes as a quite effective remedy. Applying DPPH . and ABTS + . radical scavenging and total reducing Fe(III) to Fe(II) power assays, antioxidant characteristics of both studied essential oils were estimated as weak, though of close values. Seseli rigidum fruit essential oil was proven as a potent inhibitor of human and horse serum cholinesterase, recognizing its possible application as neural protective agent.

Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum)

“…The antioxidant properties of plant-derived products have become an indispensable tool in determining their efficacy as treatments [4]. An imbalance between the synthesis and accumulation of reactive oxygen species (ROS) in cells and tissues, as well as the ability of a biological system to de-toxify these reactive products, causes oxidative stress [40].…”

“…Some representatives of Seseli genus have also been used in the treatment of central nervous system disorders such as epilepsy [3]. Furthermore, some members of the genus Seseli have been widely employed in traditional medicine owing to their antibacterial, antifungal, and insect repellent activities [4], while others are known as being antispasmodic and diuretic [5].…”

Chemical composition and cytotoxic potency of essential oil from Seseli petraeum M. Bieb. (Apiaceae)

“…Moreover, Seseli species have been used traditionally for human inflammation, swelling, rheumatism, pain, and the common cold [19]. Also, the species have been used in European traditional medicine widely, presenting antibacterial, antifungal, insect repellent, emmenagogue, antiflatulence, anti-inflammatory, antinociceptive, anti-tumor, anti-rheumatic activities, and protective effect on human lymphocytes DNA [20]. In Turkish folk medicine, S. tortuosum is used as an emmenagogue and anti-flatulence [21][22], and S. libanotis called "Kelemkeşir" or "kelemenkeşir" in Turkish, is used as a cheese preservative to provide aroma [23][24], besides the leaves of the species are consumed as a vegetable in eastern Turkey [22].…”

Sukcesije biljnih zajednica na pozaristima planine Vidlic

“…У оквиру ове докторске дисертације, поред анализе садржаја тешких метала у биљкама сагледано је и њихово присуство и у одговарајућим узорцима земљишта на опожареним и неопожареним површинама, а резултати објављени Mitić et al, 2008Mitić et al, , 2012Ilić et al, 2010Ilić et al, , 2011b). …”

“…Одређен је садржај тешких метала у узорцима биљака и земљишта са пожаришта и неопожарене површине Marković et al, 2008;Ilić et al, 2011b;Jovanović et al, 2012). Mitić et al (2012) на основу претходно објављених података о садржају тешких метала у биљним врстама са пожаришта Видлича постављају питање: Да ли шумски пожар утиче на садржај тешких метала у биљкама које се користе у народној медицини?…”