Comparison of Clinical and Functional Outcomes in One versus Two Component Revision for Total Knee Arthroplasty

Howard, L.C.; Day, Charles S.; Masri, Bassam A.; Garbuz, Donald S.

doi:10.1016/j.arth.2023.01.047

Cited by 4 publications

(1 citation statement)

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“…The increasing number of patients receiving prosthetic joint replacement surgery is driven by factors such as osteoporosis, trauma, and tumors ( Hunter and Bierma-Zeinstra, 2019 ). As the number of joint replacement surgeries rises, so do postoperative complications, including prosthesis sinking, loosening, and displacement ( Howard et al, 2023 ). Currently, over 30% of joint replacement patients undergo one or more joint replacement surgeries in 20 years ( Lee et al, 2023 ).…”

Section: Resultsmentioning

confidence: 99%

“Metal-bone” scaffold for accelerated peri-implant endosseous healing

Lu,

Wang,

Chen

et al. 2024

Front. Bioeng. Biotechnol.

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Restoring bone defects caused by conditions such as tumors, trauma, or inflammation is a significant clinical challenge. Currently, there is a need for the development of bone tissue engineering scaffolds that meet clinical standards to promote bone regeneration in these defects. In this study, we combined the porous Ti6Al4V scaffold in bone tissue engineering with advanced bone grafting techniques to create a novel “metal-bone” scaffold for enhanced bone regeneration. Utilizing 3D printing technology, we fabricated a porous Ti6Al4V scaffold with an average pore size of 789 ± 22.69 μm. The characterization and biocompatibility of the scaffold were validated through in vitro experiments. Subsequently, the scaffold was implanted into the distal femurs of experimental animals, removed after 3 months, and transformed into a “metal-bone” scaffold. When this “metal-bone” scaffold was re-implanted into bone defects in the animals, the results demonstrated that, in comparison to a plain porous Ti6Al4V scaffold, the scaffold containing bone tissue achieved accelerated early-stage bone regeneration. The experimental group exhibited more bone tissue generation in the early stages at the defect site, resulting in superior bone integration. In conclusion, the “metal-bone” scaffold, containing bone tissue, proves to be an effective bone-promoting scaffold with promising clinical applications.

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Section: Resultsmentioning

confidence: 99%