Comparison of Clinical and Physiological Parameters for Benign Prostatic Hyperplasia in Hypertensive and Normotensive Patients

Abstract

Objective: To discover the correlation of clinical and physiological measures for benign prostatic hyperplasia in hypertensive and normotensive patients.Methods: From September 2016 to October 2017, 435 patients were enrolled for further selection. The parameters evaluated for eligible patients included prostate volume, systolic blood pressure, diastolic blood pressure, international prostate symptom score, etc. Then the eligible patients were divided into two groups according to hypertension condition, and the clinical and physiological parameters were compared between two groups. The Pearson’s correlation coefficient was used to test the linearity of the relationships of these clinical and physiological components with prostate volume, total prostate specific antigen, and international prostate symptom score.Results: Finally, 350 patients were involved in this study, including 117 with hypertension and 233 without hypertension. Weight, body mass index, systolic blood pressure, and diastolic blood pressure were significantly different between the hypertension and normotension groups. In the normotension group, there were positive correlations between weight, body mass index, age, and prostate volume; between fasting blood sugar, systolic blood pressure, diastolic blood pressure, and total prostate specific antigen; between fasting blood sugar and international prostate symptom score. In the hypertension group, there were positive correlations between age and total prostate specific antigen and international prostate symptom score; between weight and prostate volume; between systolic blood pressure and total prostate specific antigen.Conclusion: This study indicated that there might be no significant association between hypertension and prostate volume.

High degree of prostate related LUTS in a prospective cross-sectional community study in Ghana (Mamprobi)

“…Similar results were obtained by others where an association was obtained between hypertension and BPH independent of age [28]. On the contrary Zeng et al [32] have proposed no association between hypertension and BPH.…”

Body Mass Index and Risk of Prostate Volume, International Prostate Symptom Score, Maximum Urinary Flow Rate, and Post-Void Residual in Benign Prostatic Hyperplasia Patients

“…This cross-sectional study was conducted and reported according to the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) statement (Vandenbroucke et al, 2014). Baseline data for this study were obtained from the Bladder Cancer and Benign Prostatic Hyperplasia Study in Chinese Population (BPSC; Zeng, Liu et al, 2018; Zeng, Weng, Jin et al, 2018; Zeng, Weng, Xiong et al, 2018), which was a prospective study to estimate interventional effect on and risk factors for bladder cancer and BPH. All participants were Chinese people and had signed an informed consent before enrollment.…”

A Preliminary, Multicenter, Prospective and Real World Study on the Hemostasis, Coagulation, and Safety of Hemocoagulase Bothrops Atrox in Patients Undergoing Transurethral Bipolar Plasmakinetic Prostatectomy

“…This study adopted a multicenter, prospective, and real world design for preliminary investigation. The subjects were selected from the Bladder Cancer and Benign Prostatic Hyperplasia Study in Chinese Population (BPSC), a prospective study reported previously (Zeng et al, 2018a; Zeng et al, 2018b; Zeng et al, 2018c; Wu et al, 2019; Zhao et al, 2019; Zi et al, 2019), which from September 2016 to November 2018. Eligible patients were confirmed with BPH and underwent TUPKP.…”