Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Abstract

Background: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy.Methods: Patients were divided into two groups as positive (PA) (n:362) and negative appendectomy (NA) (n:284) and the data obtained were compared between these two groups.Laboratory investigations were performed in all patients, and white blood cell (WBC), mean platelet volume (MPV), neutrophils count (NEU), neutrophils (%) (NEU%), C-reactive protein (CRP) and total bilirubin (TBIL) values were studied.Results: The mean MPV value was found as 7.88 fl in PA groups and 8.09 fl in NA group, and the mean MPV value was not statistically significantly difference in PA group, compared to NA groups (p=0.012). Laboratory parameters were also compared between genders. Accordingly, the mean MPV value was statistically significantly higher in female patients compared to male patients in PA group (p = 0.04). The mean TBIL value was 0.97 mg/dl in PA group and 0.69 mg/dl in NA group, and the mean TBIL value was statistically significantly higher in PA group (p< 0.001). Finally, TBIL value was statistically significantly lower in female patients compared to male patients in NA and PA group (p < 0.05).Conclusions: According to the results of our study, MPV and T. BIL values differ in PA and NA groups depending on gender. Therefore, these values may not be used as specific biomarkers in predicting positive acute appendicitis. We believe that these results will contribute to the literature and will be guiding for future studies.

Comparative Study Between Karaman Score and Modified Alvarado Score for Predictability in Avoiding Negative Appendectomy in the Suspected Cases of Acute Appendicitis

“…4 In accordance with recent guidelines, the clinical diagnosis, imaging examinations, and certain biomarkers, such as white blood cell count (WBC) and Creactive protein (CRP) levels, are all required to assess the diagnosis of acute appendicitis. 5,6 There have been fewer cases of negative appendectomies as a result of recent developments in the imaging diagnosis and the early application of computed tomography (CT). 7,8 On other hand reported that, since more than twenty years ago, magnetic resonance imaging (MRI) has been utilized for the assessment of acute appendicitis.…”