“…Currently, the way to test for HPV6 and HPV11, including genotype specific polymerase chain reaction (PCR), Quantitative real-time PCR (qPCR), polymerase chain reaction-restricted fragment length polymorphisms (PCR-RELP), droplet digital PCR (ddPCR), loop-mediated isothermal amplification (LAMP) and hybrid capture 2 test (HC2) ( Table 1 ). these kits possess high specificity and sensitivity, but require high skilled technical personnel, high cost, long detection time, well-equipped laboratories, cumbersome temperature-control devices and sophisticated analysis, which limit the wide adoption of these methods in resource-poor areas ( Grce et al., 2000 ; Hawkins et al., 2013 ; Lindh et al., 1992 ; Oliveira et al., 1994 ; Yu et al., 2015 ). Therefore, it is essential to develop a more efficient method for rapid screening of HPV6 and HPV11 infections to promote early detection and treatment.…”