OBJECTIVE: This study aims to determine the mean collum angle of maxillary central incisor and to compare it between high angle and low angle patients undergoing orthodontic treatment. METHODOLOGY: This cross-sectional, observational study was conducted using lateral cephalometric radiographs of 61 class II division 1 patients (comprised 32 males, 29 females, age range 13 to 30 years) from the record files of patients inducted for Orthodontic management from June 2020 till August 2020 at the Department of Orthodontics, Sindh Institute of Oral Health Science, Jinnah Sindh Medical University, Karachi, Pakistan. The sample was divided on the basis of Vertical Analysis (angulation of mandibular plane) into high and low angle cases. Collum angle was measured using the angulation of the Maxillary Central Incisor (MCI). Student t-test was used to compare the mean difference of the collum angle between skeletal vertical malocclusions. RESULTS: Mean value of the collum angle for high angle (Vertical Growth pattern) cases were mean ± standard deviation (4.35°±1.49°) while for low angle groups (Horizontal Growth pattern) were (2.41°±1.60°). CONCLUSION: There Collum angle of permanent maxillary central incisors differ significantly (p<0.001) among high angle and Low angle malocclusions cases (n=61) and showed pronounced axial bending in Class II division 1 incisors with high angle (4.35° ± 1.49°) as compared to low angle malocclusion (2.41° ± 1.60°). KEYWORDS: Collum Angle, Maxillary Central Incisor, Orthodontic Treatment, High Angle, Low Angle.