Comparison of continuous versus pulsed CO2 and Nd:YAG laser-induced pulmonary parenchymal lung injury in a rabbit model

Compliance and functional residual capacity after staple versus combined staple/holmium laser lung volume reduction surgery in a rabbit emphysema model

“…Increased morbidity, particularly delayed pneumothorax, has been reported in patients treated with laser LVRS compared with staple LVRS [1]. Prior laser LVRS studies in animals have demonstrated that significant lung injury occurs in normal rabbit lungs with both CO 2 and Nd:YAG laser exposure, though the clinical and histologic presentations were distinct [8,10,11]. Holmium laser exposure is more efficacious but yields no differences in morbidity compared with Nd:YAG and CO 2 exposures [7].…”