Comparison of conventional risk factors, clinical and angiographic profile between younger and older coronary heart disease patients

Khadkikar, Gajanan; Mangudkar, Sangram; Landge, Jyoti

doi:10.18203/2320-6012.ijrms20160316

Cited by 3 publications

(2 citation statements)

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“…An Indian study showed SVD in 57.1% of the patients followed by DVD in 11.5% and TVD in 7.1% cases [26]. Khadkikar GD, et al found SVD, DVD, TVD and no vessel disease among 50%, 13.6%, 4.5% and 31.8% patients respectively [27]. Colkesen AY, et al in their study on CAD in young adults also found LAD was the most commonly involved vessel, followed by RCA, LCX, and LMCA [28].…”

Section: Discussionmentioning

confidence: 97%

Untitled

2023

AVS

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Background: Coronary Artery Disease (CAD) in young and old individuals represents a special subsets that clinical profile and angiographic findings are different from older population. Better understanding of CAD in these groups of population would lead to further improvement in prevention and management. However, there are no data regarding coronary artery disease in Nigerian and Indian population. So this study was aimed to analyze the clinical profile and angiographic pattern of coronary artery disease among Nigerian and Indian patients. Methods:Retrospective study was done in 190 adults of Nigerian and Indian Origin above 18 years of age. There were 48 Nigerians and 142 Indians. These patients underwent coronary angiography between 1st May 2016 to 31st October 2017 in India and between 1st November 2017 to 31st May 2018 in Yenegoa-Nigeria. Age grouping (Group I -< 40 years, Group II-40 to 49 years, 50-59 years, 60-69 years and above 60years), clinical presentation, risk factors for CAD, angiographic findings and management strategy were analyzed.Results: Group I patients represented 2% and 18.3% among the Nigerian and Indian patients respectively. Increasing age was significantly associated with the risk of developing CAD. Risk factors in both populations included tobacco use, smoking, dyslipidemia, DM, hypertension, sendatory life style and alcohol consumption were common to both population. Eight patients of Indian origin had Takayasu disease as risk factor which was not found among the Nigerian patients. Pattern of dyslipidemia was higher among the Indian patients. CAD sets in ealier among Indian as compared to Nigerian patients. Involement of arterial vascular beds was more among the Indian than Nigerian subjects. Nigerian patients were managed with medical and PCI. The Indians subjects were manged with medical, PCI and CABG.Conclusions: Risk factors for CAD among Indians and Nigerians were similar. Takayasu disease could affect the coronary artery but rare among Nigerians. Screening for risk factors should start at an earlier age, and smoking cessation, promotion of physical activities and healthy dietary pattern have to be strongly encouraged among these group.

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Section: Discussionmentioning

confidence: 97%

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2023

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“…Khadkikar GD et al, observed SVD, DVD, TVD and no vessel disease in 50%, 13.6%, 4.5% and 31.8% of cases [19] respectively.…”

Section: Analysis Of Angiographic Findingsmentioning

confidence: 96%

Study of Risk Factors,clinical Profiles and Angiographic Patterns in Patients of Coronary Artery Disease in a Tertiary Care Centre in Kolkata

Mandal¹,

Singh²

2021

PIJR

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BACKGROUND:Coronary artery disease (CAD) is one of the most common causes of mortality and morbidity in both developed and developing countries. It is a leading cause of death in India, and its contribution to mortality is rising. Considering the increasing burden of coronary artery disease and its mortality and the usefulness of identifying risk factors, studying the clinical profile and angiographic pattern will help us intervene the disease at various levels which can help control the morbidity and mortality of coronary artery diease. MATERIALS AND METHOD: The present study was conducted in the Department of Cardiology,IPGMER & SSKM Hospital,Kolkata during the period of January 2019 to December 2019.This is a hospital based observational prospective study with prospective data collection,where all patients of coronary artery disease who had undergone coronary angiography has been taken into consideration to find out the risk factors,clinical profiles and angiographic patterns in coronary artery disease patients in Kolkata. RESULTS: Maximum patients were present in the age group 51-60 years of age.Mean age is 56.7+11.6sd.Male patients were 70% and female patients were 30%.Most common symptom was chest pain,90% of patients had it during the time of presentation.The next frequent symptom was shortness of breath which was seen in 52% of patients. Most common risk factor was smoking which was seen in 58% of patients.Next frequent risk factor being hypertension seen in 43.5% of patients.Obesity was seen in 59.2% of patients.On coronary angiography,40% of patients had Single vessel CAD,27.3% had double vessel CAD,23.5% had Double vessel CAD,6.5% had Non-Significant CAD and 2.7% had Normal coronaries(recanalized epicardial coronaries).LAD was involved in 73.5% of patients,51.7 % had RCA involved,43.5 % had LCX involved and LMCA was involved in 1.7% of patients. CONCLUSION:Smoking and hypertension are the most common risk factors.Single vessel disease is the most common angiographic pattern.Risk factors should be addressed properly to decrease the morbidity and mortality of coronary artery disease

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