Comparison of Corneal Thickness Measurements After Customized Corneal Crosslinking Using High-Resolution Optical Coherence Tomography and Scheimpflug Tomography

Baiao, Tiago Mendes; Wendelstein, Jascha; Seiler, Theo

doi:10.1097/ico.0000000000003158

Cited by 3 publications

(1 citation statement)

References 22 publications

(36 reference statements)

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“…The researchers utilized the Pentacam HR and the MS-39 AS-OCT imaging techniques to evaluate the corneal thickness measurements preoperatively and 1, 3, and 12 months. Their findings indicated that the Pentacam HR method exhibited a tendency to underestimate pachymetry measurements in cases when corneal haze was present (19). Furthermore, Ashour et al found that the Pentacam HR (Oculizer II) had a tendency to underestimate corneal thickness readings in keratoconus (KC) and scarred corneas when compared to AS-OCT.…”

Section: Discussionmentioning

confidence: 99%

Schimpflug versus Anterior Segment Optical Coherence Tomography after Epi-on Corneal Cross Linking in Keratoconus

Mohammed,

El-gazzar,

Eleiwa

et al. 2023

Benha Medical Journal

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Background:The measurement of corneal thickness is a crucial factor in evaluating keratoconus and its potential treatment methods, such as collagen cross-linking (CXL). The aim of this study was to evaluate the inter-device reliability in the corneal pachymetry following epi-on CXL using anterior segment optical coherence tomography (AS-OCT) and Scheimpflug tomography. Methods: This was across-sectional observational study that involved patients diagnosed with keratoconus and had undergone epi-on cross linking. Patients were subjected to follow-up examinations and corneal imaging with Pentacam (Oculyzer) and AS-OCT (Optovue). The interdevice reliability was assessed using the intraclass correlation coefficient (ICC) and Cronbach's alpha. Results: 72 of eyes (36 patients), aged (18-43) years with 27 (75%) males, 9(25%) females were included in the study. Regarding central corneal thickness (CCT) pentacam measured a mean of 519.18µm, versus 507.83 µm using AS-OCT, P value < 0.001. Thinnest corneal thickness (TCT) measured 511.61µm with pentacam versus 491.61 µm using AS-OCT, P value <0.001. On evaluating the agreement between pentacam and AS-OCT in measuring central corneal thickness, ICC ranged from 0.82 to 0.984, which reflected excellent reliability. Cronbach alpha was 0.975 demonstrated excellent agreement. For TCT, ICC ranged from 0.15 to 0.979, which reflected good reliability. Cronbach alpha was 0.972 demonstrated excellent agreement. Conclusion: Based on the results of corneal pachymetry, after epi-on CXL, both AS-OCT and pentacam demonstrates comparable measurements with excellent inter-device reliability. However, it is worth noting that the pentacam appears to slightly overestimates the CCT and TCT.

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Section: Discussionmentioning

confidence: 99%

Schimpflug versus Anterior Segment Optical Coherence Tomography after Epi-on Corneal Cross Linking in Keratoconus

Mohammed,

El-gazzar,

Eleiwa

et al. 2023

Benha Medical Journal

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The Influence of Lens Position, Vault Prediction, and Posterior Cornea on Phakic Posterior Chamber Intraocular Lens Power

WENDELSTEIN,

YEO,

HINTERBERGER

et al. 2024

American Journal of Ophthalmology

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Keratometry Changes Between Year One to Seven After Corneal Cross-Linking in Patients With Keratoconus

Neuhann,

Vogel,

Hall

et al. 2024

Cornea

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Purpose: We evaluated the timing at and extent to which midterm to long-term keratometric changes can occur in year 1 to 7 after corneal collagen cross-linking (CXL) in patients with keratoconus. Methods: We conducted a subgroup analysis of a retrospective cohort study of all consecutive patients who underwent CXL at our cornea center between 2007 and 2011. The inclusion criteria comprised CXL according to the Dresden protocol and a full set of keratometry parameters collected by Scheimpflug tomography preoperatively and at year 1, 3, 5, and 7 after CXL. In addition, best-corrected visual acuity was evaluated. Results: Sixty-three eyes of 47 patients were enrolled. Mean age was 25.46 years ±7.39 years (80.9% male patients). All relevant keratometric parameters showed significant improvement at year 1 after CXL (except for posterior astigmatism). According to mixed-effects model analysis, they all showed further significant change at different points in time between year 1, 3, 5, and 7 (except for K1). In addition, best-corrected visual acuity improved statistically significant between year 1, 3, 5, and 7. Suspected disease progression was noted in 22.2% of patients, mostly between year 1 and 3 after CXL. Conclusions: After initial improvement 1 year after CXL, keratometric and functional parameters were stable until year 5 after CXL in most cases; further improvement can take place even after up to 7 years post-CXL. By contrast, in case of disease progression, changes seem to occur already between year 1 and 3 after CXL.

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Comparison of Corneal Thickness Measurements After Customized Corneal Crosslinking Using High-Resolution Optical Coherence Tomography and Scheimpflug Tomography

Cited by 3 publications

References 22 publications

Schimpflug versus Anterior Segment Optical Coherence Tomography after Epi-on Corneal Cross Linking in Keratoconus

Schimpflug versus Anterior Segment Optical Coherence Tomography after Epi-on Corneal Cross Linking in Keratoconus

The Influence of Lens Position, Vault Prediction, and Posterior Cornea on Phakic Posterior Chamber Intraocular Lens Power

Keratometry Changes Between Year One to Seven After Corneal Cross-Linking in Patients With Keratoconus

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