Comparison of demographic and clinical characteristics influencing health-related quality of life in patients with diabetic foot ulcers and those without foot ulcers

Yekta, Zahra; Pourali, Reza; Ghasemi-Rad, Mohammad

doi:10.2147/dmso.s27050

Cited by 55 publications

(59 citation statements)

References 22 publications

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“…The patients in the age group of 51-60 years were most significantly infected with diabetic foot infections. The findings of this study are similar to the one reported by Yekta et al [23] in which patients in the age group of above 50 years compared to less than 50 years and the mean age of the patients were 60.73 ± 11.3 years. The main reason attributed to this is mainly due to their physical conditions along with the associated other factors of the patients in this age group.…”

Section: Discussionsupporting

confidence: 92%

Prevalence of yeast in diabetic foot infections

Sugandhi

Prasanth

2016

Int J Diabetes Dev Ctries

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Diabetic foot infections are a serious threat which cause a long term of hospitalization of diabetes patients and lead to amputations. Hence, prompt diagnosis is an important criterion in the treatment of these infections. This study was carried out to determine the prevalence of yeast in diabetic foot infections. The pus samples were collected from patients presenting with diabetic foot ulcer and processed for microbiological investigation. The patients investigated comprised of 82 males and 78 females. Most of the patients were grade I ulcers followed by grade II ulcers. Out of 160 samples, 138 samples were culture positive, in which yeast isolate Candida glabrata was the predominant isolate followed by Candida albicans, Candida dubliniensis, Candida krusei and Candida tropicalis. C. albicans and C. dubliniensis were differentiated by using tobacco agar due to the presence of hyphal fringes. The methylene blue sabouraud dextrose agar and corn meal agar were also used to differentiate C. albicans from non albicans. The antifungal susceptibility pattern showed 29 % of C. albicans was sensitive to Amphotericin B and Clotrimazole, while 75 % of C. glabrata was sensitive to Amphotericin B, Ketoconazole and Itraconazole. C. dublinensis and C. albicans showed the highest percentage of resistant to Ketoconazole, Fluconazole, Nystatin and Itraconazole. Thus, the results indicating that effective alternate drug of choice are required and the proper selection of antifungal agents will play an important role for the treatment of fungal foot infections. This study will also add substantial knowledge of yeast as one of the pathogenic organisms in diabetic foot infections.

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Section: Discussionsupporting

confidence: 92%

Prevalence of yeast in diabetic foot infections

Sugandhi

Prasanth

2016

Int J Diabetes Dev Ctries

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“…28,29 To promote QoL among thalassemic patients, a variety of factors should be taken into account by health-related policymakers, with special attention to patients presenting any comorbid diseases, poor compliance with iron-chelating therapy and lower socioeconomic status. Psychosocial support should be scheduled for patients and their families in order to prevent mental health issues, behavioral problems and illness complications.…”

Section: Discussionmentioning

confidence: 99%

Quality of life among Iranian patients with beta-thalassemia major using the SF-36 questionnaire

et al. 2013

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CONTEXT AND OBJECTIVE: Patients with beta-thalassemia major (β-TM) experience physical, psychological and social problems that lead to decreased quality of life (QoL). The aim here was to measure health-related QoL and its determinants among patients with β-TM, using the Short Form-36 (SF-36) questionnaire. DESIGN AND SETTING: Cross-sectional study at the Hematology Research Center of Shiraz University of Medical Sciences, in southern Iran. METHODS: One hundred and one patients with β-TM were randomly selected. After the participants' demographics and disease characteristics had been recorded, they were asked to fill out the SF-36 questionnaire. The correlations of clinical and demographic factors with the QoL score were evaluated. RESULTS: There were 44 men and 57 women of mean age 19.52 ± 4.3 years (range 12-38). On two scales, pain (P = 0.041) and emotional role (P = 0.009), the women showed significantly lower scores than the men. Lower income, poor compliance with iron-chelating therapy and presence of comorbidities were significantly correlated with lower SF-36 scores. These factors were also found to be determinants of worse SF-36 scores in multivariate analysis. CONCLUSIONS: We showed that the presence of disease complications, poor compliance with ironchelating therapy and poor economic status were predictors of worse QoL among patients with β-TM. Prevention and proper management of disease-related complications, increased knowledge among patients regarding the importance of managing comorbidities and greater compliance with iron-chelating therapy, along with psychosocial and financial support, could help these patients to cope better with this chronic disease state. RESUMO

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“…Another study from Saudi Arabia suggested different mechanisms of elevated cardiovascular risk between men and women: in women, elevated IL‐6 and C‐reactive protein predicted insulin resistance and hypertension, respectively, while these relationships did not hold for men . Health‐related quality of life was lower in female vs. male type 2 diabetes patients in Iran .…”

Section: Methodsmentioning

confidence: 99%