Comparison of different doses of remifentanil on the cardiovascular response to laryngoscopy and tracheal intubation

Hall, Andrew P.; Thompson, J. P.; Leslie, N. A. P.; Fox, Andrew; Kumar, Naveen; Rowbotham, D. J.

doi:10.1093/oxfordjournals.bja.a013362

Cited by 111 publications

(67 citation statements)

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“…They used the propofol 0.5 mg/kg followed by 10 mg every 10 s until loss of verbal contact. The present results are consistent with the suppression of remifentanil 0.5 μg/kg/min shown by Miyake et al but are not consistent with the report by Hall et al that infusion of remifentanil 0.25 μg/kg/min suppressed the pressure response to tracheal intubation [18]. The reason for the suppression by low-dose remifentanil seems to be the use of 1% isoflurane and 67% nitrous oxide [18].…”

Section: Discussionsupporting

confidence: 72%

Comparison of Hemodynamic Responses Associated with Tracheal Intubation Under Various Induction Doses of Remifentanil and Propofol

Goyagi¹,

Yoshimoto²

2012

OJAnes

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Background: The optimal dose of propofol and remifentanil induction to minimize the cardiovascular response associated with tracheal intubation may exist. We investigated the cardiovascular response associated with tracheal intubation when various continuous induction doses of remifentanil in combination with propofol were used. Methods: Seventyfive patients were randomly allocated into 1 of 3 groups: the R-0.4 P-1 group (remifentanil 0.4 μg/kg/min and propofol 1 mg/kg); the R-0.5 P-1 group (remifentanil 0.5 μg/kg/min and propofol 1 mg/kg); and the R-0.4 P-2 group (remifentanil 0.4 μg/kg/min and propofol 2 mg/kg). One minute after remifentanil infusion commenced, a bolus of propofol was injected. Rocuronium 1 mg/kg was administered 1 min after propofol injection following loss of consciousness. Controlled ventilation was then performed for 2 min, and the trachea was intubated 4 min after the start of the remifentanil infusion. The infusion rate of remifentanil was decreased to 0.1 μg/kg/min after intubation. Blood pressure (BP) and heart rate (HR) were measured during this period until 5 min after tracheal intubation. Results: The changes in BP response due to tracheal intubation in the R-0.4 P-1 group were greater than those in the other 2 groups, whereas the HR responses to tracheal intubation were similar among the 3 groups. Conclusion: The combination of remifentanil 0.4 μg/kg/min and propofol 1 mg/kg led to an exaggerated cardiovascular response to tracheal intubation compared with the other combination groups.

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Section: Discussionsupporting

confidence: 72%

Comparison of Hemodynamic Responses Associated with Tracheal Intubation Under Various Induction Doses of Remifentanil and Propofol

Goyagi¹,

Yoshimoto²

2012

OJAnes

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“…However, the shape of the stylet may hinder its removal and cause longer intubation times. In addition, a recent study showed that intubation times with video laryngoscopes can be decreased with proper preparation of the stylet and tracheal tube (7,27 Various studies indicated that laryngoscopy may cause an undesirable increase in blood pressure and heart rate in anesthetized patients (29)(30)(31)(32)(33)(34)(35). Various video laryngoscopes have been studied to elucidate the hemodynamic changes during orotracheal intubation; however, there has been no study comparing the hemodynamic response to orotracheal intubation of the McGrath Series 5 video laryngoscope and the Macintosh laryngoscope (36)(37)(38)(39).…”

Section: Discussionmentioning

confidence: 99%

The McGrath Series 5 video laryngoscope versus the Macintosh laryngoscope: a randomized trial in obstetric patients

Aydın

Çakmakçı

2014

Turk J Med Sci

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The utilisation of whey is very important for preventing the waste of a protein-and lactose-rich dairy by product and protecting the environment. Therefore, the objective of this study was to investigate the effect of whey use in tel (wire) kadayıf (a Turkish dessert raw material) production on microbiological and technological properties and sensory characteristics of tel kadayıf. For this purpose, 3 experimental tel kadayıf samples were produced using different amounts (0%, 25%, and 50%) of fresh whey instead of water in the production of raw tel kadayıf. The samples were placed in plastic bags and vacuum packaging and stored in a refrigerator (4 °C). Storage period (1, 3, 5, and 7 days) analysis was performed. The results of the research showed that nutritional value and sweetness increased, while the baking time decreased with respect to increases in the amount of whey used in tel kadayıf. As a result of a collective evaluation of the study findings, it was concluded that a 25% whey addition and vacuum packaging would provide the most positive quality characteristics in tel kadayıf desserts.

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“…Fifteen minutes later, remifentanil (R) was injected intraperitoneally (low dose; 0.5 µg kg -1 ) to rats in the remifentanil groups [6]. After anaesthesia, each rat was confined in a transparent pliant retention box, which impaired deambulation but left the head and tail free.…”

Section: Methodsmentioning

confidence: 99%

The Effects of Transcranial Electrical Stimulation on Anaesthesia and Analgesia in Rats

Kabalak¹,

Akçay²,

Ceylan³

et al. 2005

The Journal of Veterinary Medical Science

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ABSTRACT. In this study, we determined the effects of transcranial electrical stimulation (TCES) on the anaesthetic requirements of thiopental and the analgesic requirements of remifentanil, in rats. The experiments were performed on 120 albino male Wistar rats, which were randomly allocated to four groups (n=30). (Thiopental, Thiopental+TCES, Thiopental+Remifentanil, and Thiopental+Remifenta-nil+TCES). Animals were anaesthetized with thiopental, and 15 min later, remifentanil was injected to rats in the Remifentanil groups. TCES was started in the stimulated groups 20 min after thiopental administration. Rats were stimulated 5 times for this experiment. The times for recovery, herein called Cognition Recovery Time and Motion Recovery Time were measured. Cognition Recovery and Motion Recovery Times were not affected by the stimulation. Analgesia was assessed using the wet tail-flick latency (TFL). In the Thiopental group, the analgesia level returned to control values on the 35th min. In the Thiopental+Remifentanil group, the analgesia level returned to control values on the 50th min. In the Thiopental+ TCES group, the analgesia level reached the peak value on the 65th min. In the Thiopental+Remifentanil+TCES group, the analgesia level reached the peak value on the 35th min and analgesia remained high during the 90 min after cessation of the stimulation. The analgesic potency for the Thiopental+Remifentanil+TCES group was increased by 30-40% when compared with the prior TFL values, 160% when compared with the control group, and 50-75% when compared with Thiopental+ TCES group on the 35th min (P<0.001). In conclusion, TCES markedly decreases the anaesthetic and analgesic requirements for thiopental and remifentanil in rats.

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Comparison of different doses of remifentanil on the cardiovascular response to laryngoscopy and tracheal intubation

Cited by 111 publications

References 0 publications

Comparison of Hemodynamic Responses Associated with Tracheal Intubation Under Various Induction Doses of Remifentanil and Propofol

Comparison of Hemodynamic Responses Associated with Tracheal Intubation Under Various Induction Doses of Remifentanil and Propofol

The McGrath Series 5 video laryngoscope versus the Macintosh laryngoscope: a randomized trial in obstetric patients

The Effects of Transcranial Electrical Stimulation on Anaesthesia and Analgesia in Rats

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