Comparison of different sample preparation procedures for multiclass determination of selected veterinary drug, coccidiostat and insecticide residues in eggs by liquid chromatography-tandem mass spectrometry

Abstract

QuEChERS and zirconium-coated silica SPE in a multiresidue method for the analysis of veterinary drug residues and other contaminates in eggs by LC-MS/MS.

Detection, Occurrence and Fate of Emerging Contaminants in Agricultural Environments

“…Piatkowska et al (2014) compared various sample extraction and clean-up techniques for the simultaneous analyses of multi-class veterinary pharmaceuticals in food products and environmental samples. The classes of antibiotics included: sulphonamides, fluoroquinolones, tetracyclines, macrolides, penicilines, cephalosporins, nitroimidazoles, benzimidazoles, coccidiostats, amphenicoles, and insecticides as well as tiamulin and lincomycin.…”

A novel method based on MSPD for simultaneous determination of 16 pesticide residues in tea by LC–MS/MS

“…PSA, a weak anion exchanger which strongly interacts with various polar organic acids, was chosen as the sorbent in most cases [11,43]. Sterols and pigments such as chlorophyll can be absorbed by GCB [11].…”

Ultrasound-assisted dispersive liquid–liquid microextraction of tetracycline drugs from egg supplements before flow injection analysis coupled to a liquid waveguide capillary cell

“…The most important are solvent extraction [5,16], liquid-liquid extraction (LLE) [3], solidphase extraction (SPE) [1,2,4,5,11,14,15,17,19], ultrasonic-assisted extraction (UAE) [2], and pressurized liquid extraction (PLE) [6,12]. Furthermore, SPE modifications using molecularly imprinted solid-phase extraction (MISPE) [13,20] and magnetic molecularly imprinted polymer solidphase extraction (MIP-SPE) [18] have also been used as extraction methods.…”

“…Tetracycline antibiotics are poorly metabolized in animals and unsafe levels of drug residues can therefore be present in foods such as meat, fish, honey, milk, and eggs, as well as in products derived from them [3,4]. Eggs are an inexpensive animal-derived food that is readily available and has high nutritional value [5], and the presence of contaminants is not permitted.…”

“…The analytical techniques reported in the literature for the monitoring and determination of tetracycline antibiotics and other veterinary drugs in eggs are mostly chromatographic, including high performance liquid chromatography (HPLC) with ultraviolet (UV) [7,[11][12][13], fluorescence [14], or mass spectrometry (MS/MS) [1][2][3][4][15][16][17][18][19][20] detection, and ultrahigh-pressure liquid chromatography-tandem mass spectrometry (UHPL-MS/MS) [5,6].…”