Comparison of disinfectant efficacy when using high‐volume directed mist application of accelerated hydrogen peroxide and peroxymonosulfate disinfectants in a large animal hospital

Saklou, Nadia T.; Burgess, Brandy A.; Metre, David C. Van; Hornig, Katlin J.; Morley, Paul S.; Byers, Stacey R.

doi:10.1111/evj.12476

Cited by 17 publications

(14 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A recent paper examining disinfection efficacy against several common bacterial pathogens in a large animal hospital environment showed an approximately 90% reduction in colony-forming units per milliliter of S enterica when either an accelerated hydrogen peroxide or peroxy monosulfate disinfectant product was used via a mist application technique, provided adequate cleaning was performed first. 46 As with antimicrobial drugs, disinfectants have a spectrum of activity that can be highly variable between disinfectant classes. 1 Examples of disinfectants commonly used in veterinary medicine include bleach (sodium hypochlorite), quaternary ammonium, phenols, and peroxides.…”

Section: Prevention and Control Adult Cowsmentioning

confidence: 99%

“…The principle advantage of phenols is better activity in organic debris. Peroxides are increasingly used for environmental disinfection, footbaths, and environmental misting and fogging, 1,46 and are perceived as being more environmentally friendly than chemicals such as phenols and bleach. Chlorine dioxide is a powerful oxidant as well as disinfectant, and it can be used to remove and prevent biofilm formation.…”

Section: Prevention and Control Adult Cowsmentioning

confidence: 99%

See 1 more Smart Citation

Salmonella in Dairy Cattle

Holschbach

Peek

2018

Veterinary Clinics of North America: Food Animal Practice

117

118

View full text Add to dashboard Cite

As an infectious, contagious pathogen, Salmonella is probably rivaled by only bovine viral diarrhea virus in its ability to cause clinical disease, such as enteritis, septicemia, pneumonia, and reproductive losses. The increasing prevalence of Salmonella, particularly Salmonella Dublin, on dairies presents new challenges to producers and veterinarians. No current discussion of bovine salmonellosis is complete without acknowledging the increasing public health concern. Increasing antimicrobial resistance among enteric pathogens brings the use of antimicrobials by veterinarians and producers under ever stricter scrutiny. This article provides a comprehensive review of Salmonella etiology, prevalence, pathogenesis, diagnostics, treatment, and control.

show abstract

Section: Prevention and Control Adult Cowsmentioning

confidence: 99%

Section: Prevention and Control Adult Cowsmentioning

confidence: 99%

Salmonella in Dairy Cattle

Holschbach

Peek

2018

Veterinary Clinics of North America: Food Animal Practice

117

118

View full text Add to dashboard Cite

show abstract

“…Thus, the disinfection of the livestock and poultry houses has become an important measure to prevent and control diseases. The commonly used chemical disinfectants for broiler houses include available chlorine, ozone, quaternary ammonium salt, and glutaraldehyde ( Meroz and Samberg, 1995 ; Saklou et al, 2016 ; Chidambaranathan and Balasubramanium, 2017 ). The different disinfectants used for large-scale disinfection of broiler houses operate via different mechanisms, and thus, their disinfection efficacies also differ ( Suwa et al, 2013 ; Chidambaranathan and Balasubramanium, 2017 ; Maertens et al, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

“…Aerosolized disinfectants have been applied for more than half a century. Aerosol can conserve materials and form a disinfecting aerosol-disinfectant vapor gas system ( Wichelhaus et al, 2006 ; Carvalho et al, 2015 ; Saklou et al, 2016 ). With the application of ultrasonic atomization technology, liquids can be atomized into an aerosol state to obtain uniformly dispersed 2–4 μm droplets.…”

Section: Introductionmentioning

confidence: 99%

Effect of Different Disinfectants on Bacterial Aerosol Diversity in Poultry Houses

Jiang

Tang

et al. 2018

Front. Microbiol.

View full text Add to dashboard Cite

To better understand the effect of different disinfectants on the types and quantities of microorganisms in a broiler chicken house, five different types of disinfectants, including ozone, available chlorine, quaternary ammonium salt, glutaraldehyde, and mixed disinfectant, were used. The broiler house microbial communities were analyzed by high-throughput sequencing combined with air sampling. The results showed that the concentrations of airborne aerobic bacteria in the empty broiler houses after application of different disinfectants were significantly reduced compared to a house untreated with disinfectant (P < 0.05 or P < 0.01), and the number of inhalable particles of airborne aerobic bacteria sharply decreased after disinfection. Of the five disinfectants, the mixed disinfectant had the best disinfection efficacy on the total microbial communities (P < 0.05). A total of 508,143 high-quality sequences were obtained by high-throughput sequencing, which identified 1995 operational taxonomic units. In total, 42 phyla and 312 genera were identified. The structures of airborne microbial communities in the broiler houses after the different disinfectants were applied differed. In the house treated with the mixed disinfectant, the microbial communities containing opportunistic pathogens, such as Escherichia-Shigella, Bacillus, and Pseudomonas, had the lowest abundance, with a significant decrease compared to the house untreated with disinfectant. The alpha diversity index showed low diversity of the microbial communities in the house treated with mixed disinfectant. In contrast to the other four disinfectants, only a small amount of bacteria was detected in the air sample in the house treated with the mixed disinfectant; specifically, only four phyla were found (Proteobacteria, Bacteroidetes, Actinobacteria, and Firmicutes). The mixed disinfectant produced a positive effect on disinfection for four phyla; however, it didn’t thoroughly eliminate them. At genus level, Bacillus, Arenimonas, and Shinella could not be detected in the house treated with the mixed disinfectant, but were detected in houses treated with other disinfectants. The high-throughput sequencing results revealed that the combination of multiple disinfectants exhibited a good disinfection efficacy and that this technique could disinfect the air of broiler houses. These results will help guide the development of a reasonable program for broiler house disinfection.

show abstract

“…Recently, a new peroxygen disinfectant, 4.25% hydrogen peroxide, has become available that the manufacturer reports to have broad antimicrobial activity (labeled as a broad‐spectrum fungicide, virucide, and bacteriocide), and anecdotally is reportedly to be less corrosive on surfaces. We have shown that this product is comparable to other commonly used disinfectants in a directed mist application . However, there currently are no published reports evaluating this product in a footmat application.…”

mentioning

confidence: 76%

Evaluation of the Efficacy of Disinfectant Footmats for the Reduction of Bacterial Contamination on Footwear in a Large Animal Veterinary Hospital

Hornig

Burgess

Saklou

et al. 2016

Veterinary Internal Medicne

View full text Add to dashboard Cite

BackgroundInfection control is critical to providing high‐quality patient care. Many veterinary teaching hospitals (VTHs) utilize footbaths or footmats at entrances and key control points throughout the facility to decrease trafficking of pathogenic microorganism on contaminated footwear.Hypothesis/ObjectivesTo compare efficacy of 4 disinfectants used in footmats for decreasing bacterial contamination of footwear in a large animal hospital.AnimalsA single adult dairy cow was housed in a stall for 4 days to facilitate stall contamination with fecal material.MethodsOverboots were experimentally contaminated with organic material in a standardized manner. Each boot was randomly assigned to 1 of 5 treatments (no treatment, or exposure to 1 of 4 disinfectants: an accelerated peroxygen [AHP], a peroxygen [VIRKON], a quaternary ammonium [QUAT], and a phenolic disinfectant [PHENOLIC]) by stepping on a soaked footmat and collecting samples from boot soles. Generalized linear modeling was used to analyze differences in bacterial counts.ResultsReductions in colony‐forming units (CFUs) on treated boots ranged from no detectable reduction to 0.45 log10 and varied by disinfectant. Percentage reductions in total bacterial counts generally were larger (albeit still modest) for AHP and QUAT disinfectants (range 37–45%) and smallest for the PHENOLIC (no detectable reduction).Conclusions and Clinical ImportanceIn general, use of disinfectant footmats was associated with significant reductions in viable bacteria on overboots—albeit with variable efficacy. Footmats may be useful adjuncts to cleaning and disinfection programs for decreasing trafficking of microorganisms throughout VTHs but should not be considered as a sole prevention method.

show abstract

Comparison of disinfectant efficacy when using high‐volume directed mist application of accelerated hydrogen peroxide and peroxymonosulfate disinfectants in a large animal hospital

Cited by 17 publications

References 10 publications

Salmonella in Dairy Cattle

Salmonella in Dairy Cattle

Effect of Different Disinfectants on Bacterial Aerosol Diversity in Poultry Houses

Evaluation of the Efficacy of Disinfectant Footmats for the Reduction of Bacterial Contamination on Footwear in a Large Animal Veterinary Hospital

Contact Info

Product

Resources

About